Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

Myeloperoxidase anticorps (FITC)

MPO Reactivité: Humain FACS Hôte: Souris Monoclonal MPO421-8B2 FITC
N° du produit ABIN2749159
  • Antigène Voir toutes Myeloperoxidase (MPO) Anticorps
    Myeloperoxidase (MPO)
    Reactivité
    • 174
    • 64
    • 56
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 132
    • 77
    • 1
    • 1
    • 1
    Souris
    Clonalité
    • 121
    • 91
    Monoclonal
    Conjugué
    • 93
    • 31
    • 30
    • 12
    • 10
    • 10
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Myeloperoxidase est conjugé à/à la FITC
    Application
    • 124
    • 86
    • 62
    • 62
    • 33
    • 29
    • 27
    • 19
    • 16
    • 14
    • 14
    • 13
    • 10
    • 8
    • 7
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Specificité
    The mouse monoclonal antibody MPO421-8B2 recognizes human myeloperoxidase, a heme protein present in intracellular granules of myeloblasts, neutrophils and monocytes. It is a marker of acute myelogenous leukemias and acute lymphoblastic leukemias.
    Réactivité croisée (Details)
    Human
    Purification
    Purified antibody is conjugated with fluorescein isothiocyanate (FITC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
    Immunogène
    Human myeloperoxidase
    Clone
    MPO421-8B2
    Isotype
    IgG1
    Top Product
    Discover our top product MPO Anticorps primaire
  • Indications d'application
    Flow cytometry: The reagent is designed for analysis of human blood cells using 4 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests. Intracellular staining.
    Commentaires

    The purified antibody is conjugated with Fluorescein isothiocyanate (FITC) under optimum conditions. The reagent is free of unconjugated FITC and adjusted for direct use. No reconstitution is necessary.

    Restrictions
    For Research Use only
  • Buffer
    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Stockage commentaire
    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • Antigène
    Myeloperoxidase (MPO)
    Abstract
    MPO Produits
    Synonymes
    anticorps mKIAA4033, anticorps MPO, anticorps LOC100335032, anticorps POX2', anticorps XPOX2', anticorps mpo, anticorps mpo-A, anticorps pmr-1, anticorps pmr1, anticorps pox2, anticorps xpox2, anticorps myeloperoxidase, anticorps myeloperoxidase L homeolog, anticorps MPO, anticorps Mpo, anticorps LOC100335032, anticorps mpo.L
    Sujet
    Myeloperoxidase,Myeloperoxidase (MPO) is a heme enzyme that is localized in azurophilic (primary) granules of myeloid cells and its synthesis occurs at an early stage of differentiation. The mature myeloperoxidase is a tetramer composed of two light (12 kDa) and two heavy (60 kDa) chains. This enzyme uses hydrogen peroxide to oxidize numerous substrates, including serotonin, melatonin or chloride, to produce reactive free radicals that contribute to immune reactions of myeloid cells against pathogens. Myeloperoxidase functions not only in host defense by mediating efficient microbial killing but also can contribute to progressive tissue damage in chronic inflammatory states such as atherosclerosis or acute pancreatitis.,MPO
    ID gène
    4353
    UniProt
    P05164
    Pathways
    Chromatin Binding
Vous êtes ici:
Support technique