CCR3 anticorps

N° du produit ABIN2749182

Il existe 1 publication pour ce produit. L’anticorps anti-CCR3 Monoclonal Souris est utilisé pour la détection de CCR3 dans des échantillons de Humain. Il a été validé pour FACS.

Aperçu rapide pour CCR3 anticorps (ABIN2749182)

Antigène: CCR3 (Chemokine (C-C Motif) Receptor 3 (CCR3))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CCR3 est non-conjugé

Application: Flow Cytometry (FACS)

Clone: 5E8

Détail du produit anti-CCR3 anticorps

Fonction: Anti-Hu CD193 Purified

Réactivité croisée (Details): Human

Attributs du produit: The mouse monoclonal antibody 5E8 recognizes an extracellular epitope of CD193 (chemokine receptor 3), an approximately 41 kDa protein expressed above all in eosinophils and basophils.

Purification: Purified by protein-A affinity chromatography.

Pureté: > 95 % (by SDS-PAGE)

Immunogène: human CD193 transfectants

Isotype: IgG2b, kappa

Information d'application

Indications d'application: Flow cytometry: Recommended dilution: 1-4 μg/mL.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Do not freeze

Stock: 4 °C

Stockage commentaire: Store at 2-8°C. Do not freeze.

Références pour anticorps anti-CCR3 (ABIN2749182)

Morshed, Hlushchuk, Simon, Walls, Obata-Ninomiya, Karasuyama, Djonov, Eggel, Kaufmann, Simon, Yousefi: "NADPH oxidase-independent formation of extracellular DNA traps by basophils." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 192, Issue 11, pp. 5314-23, (2014) (PubMed).

Détails sur CCR3

Antigène: CCR3 (Chemokine (C-C Motif) Receptor 3 (CCR3))

Autre désignation: CD193

Sujet: C-C motif chemokine receptor 3,CD193 / CCR3 is a G-protein coupled receptor for several chemokines, namely CCL11 (eotaxin), CCL26 (eotaxin-3), CCL7 (MCP-4), or CCL5 (RANTES). It is highly expressed on eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. CD193 is the key eosinophil chemokine receptor responsible for regulation of eosinophil migration and function. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1.,CCR3, CKR3, CMKBR3, CC-CKR-3

ID gène: 1232

UniProt: P51677