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CD99 anticorps (APC)

CD99 Reactivité: Humain FACS Hôte: Souris Monoclonal 3B2-TA8 APC
N° du produit ABIN2749207
  • Antigène Voir toutes CD99 Anticorps
    CD99
    Reactivité
    • 99
    • 25
    • 10
    • 6
    • 1
    Humain
    Hôte
    • 75
    • 44
    • 5
    Souris
    Clonalité
    • 67
    • 57
    Monoclonal
    Conjugué
    • 50
    • 11
    • 9
    • 8
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CD99 est conjugé à/à la APC
    Application
    • 60
    • 55
    • 37
    • 28
    • 22
    • 18
    • 14
    • 14
    • 13
    • 12
    • 7
    • 5
    • 4
    • 1
    Flow Cytometry (FACS)
    Specificité
    The mouse monoclonal antibody 3B2/TA8 recognizes CD99, an approximately 32 kDa sialoglycoprotein expressed on the surface of many cell types, with particularly strong expression on Ewing´s sarcoma and peripheral primitive neuroectodermal tumors. Within the hematopoietic system, CD99 is expressed on virtually all cell types except granulocytes.
    Réactivité croisée (Details)
    Human
    Purification
    Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
    Immunogène
    Human thymocytes
    Clone
    3B2-TA8
    Isotype
    IgG2a kappa
    Top Product
    Discover our top product CD99 Anticorps primaire
  • Indications d'application
    Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
    Commentaires

    The purified antibody is conjugated with cross-linked Allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.

    Restrictions
    For Research Use only
  • Buffer
    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Stockage commentaire
    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • Brémond, Meynet, Mahiddine, Coito, Tichet, Scotlandi, Breittmayer, Gounon, Gleeson, Bernard, Bernard: "Regulation of HLA class I surface expression requires CD99 and p230/golgin-245 interaction." dans: Blood, Vol. 113, Issue 2, pp. 347-57, (2009) (PubMed).

    Kueng, Leb, Haiderer, Raposo, Thery, Derdak, Schmetterer, Neunkirchner, Sillaber, Seed, Pickl: "General strategy for decoration of enveloped viruses with functionally active lipid-modified cytokines." dans: Journal of virology, Vol. 81, Issue 16, pp. 8666-76, (2007) (PubMed).

    Waclavicek, Majdic, Stulnig, Berger, Sunder-Plassmann, Zlabinger, Baumruker, Stöckl, Ebner, Knapp, Pickl: "CD99 engagement on human peripheral blood T cells results in TCR/CD3-dependent cellular activation and allows for Th1-restricted cytokine production." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 161, Issue 9, pp. 4671-8, (1998) (PubMed).

  • Antigène
    CD99
    Autre désignation
    CD99 (CD99 Produits)
    Synonymes
    anticorps 1110061M03Rik, anticorps 2410026K10Rik, anticorps D4, anticorps Pilr-l, anticorps pilr-1, anticorps HBA71, anticorps MIC2, anticorps MIC2X, anticorps MIC2Y, anticorps MSK5X, anticorps CD99 antigen, anticorps CD99 molecule (Xg blood group), anticorps CD99 molecule, anticorps Cd99, anticorps CD99
    Classe de substances
    Viral Protein
    Sujet
    CD99 Molecule (Xg blood group),CD99 is a ubiquitous transmembrane type I sialoglycoprotein of a unique and poorly characterized protein family. CD99 is heavily O-glycosylated and was described as a T cell costimulator and strong activator of integrin-mediated actin cytoskeleton assembly, promoting cell adhesion and homotypic aggregation, immediate arrest on an inflamed vascular endothelium, and cell migration through it. Ligation of CD99 under some conditions can lead to apoptosis. Originally CD99 was described as a human thymus leukemia antigen, an Ewing´s sarcoma-specific membrane marker, and an adhesion molecule involved in spontaneous rosette formation of T cells with erythrocytes.,MIC2, HBA71, blood group Xg
    ID gène
    4267
    UniProt
    P14209
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