FBLN3 anticorps

N° du produit ABIN2763849

Cet anticorps anti-FBLN3 est un anticorps Lapin Polyclonal détectant FBLN3 dans WB, IHC et EIA. Adapté pour Humain.

Aperçu rapide pour FBLN3 anticorps (ABIN2763849)

Antigène: FBLN3 (Fibulin 3 (FBLN3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FBLN3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Enzyme Immunoassay (EIA)

Détail du produit anti-FBLN3 anticorps

Réactivité croisée: Humain

Attributs du produit: EGF-containing fibulin-like extracellular matrix protein 1, Extracellular protein S1-5, Fibulin-like protein, EFEMP1,Fibulin-1 is a modular glycoprotein component of elastic extracellular matrix fibers, basement membranes and blood. It can bind calcium, Fibronectin, Laminin, Nidogen and Fibrinogen. Estrogen exposure to ovarian cancer cell lines can upregulate Fibulin-1. Fibulin-2 is abundant in heart, placenta and ovarian tissue and binds several components of the extracelllar matrix including aggrecan, versican and brevican. Fibulin-3, also known as EFEMP1, is a secreted protein. Defects in the gene for Fibulin-3 cause the autosomal dominant disease Doyne honeycomb retinal dystrophy (DHRD, also known as malattia leventinese) which is characterized by yellow-white deposits (drusen) that accumulate under the retinal pigment epithelium. Fibulin-3 is not present at the site of drusen formation in normal eyes. Fibulin-5 is an integrin-binding extracellular matrix protein that mediates endothelial cell adhesion.

Purification: Antigen Immunoaffiinity Purification

Immunogène: Synthetic peptide derived from human fibulin-3 protein

Isotype: IgG

Information d'application

Indications d'application: Optimal concentration should be evaluated by serial dilutions.

Restrictions: For Research Use only

Stockage

Buffer: Provided as solution in phosphate buffered saline with 0.08 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Détails sur FBLN3

Antigène: FBLN3 (Fibulin 3 (FBLN3))

Autre désignation: Fibulin-3

UniProt: Q12805

Pathways: EGFR Signaling Pathway