HCRTR1 anticorps (N-Term)

N° du produit ABIN2764055

L’anticorps anti-HCRTR1 Polyclonal Lapin est utilisé pour la détection de HCRTR1 dans des échantillons de Humain. Il a été validé pour ELISA.

Aperçu rapide pour HCRTR1 anticorps (N-Term) (ABIN2764055)

Antigène: HCRTR1 (Hypocretin (Orexin) Receptor 1 (HCRTR1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HCRTR1 est non-conjugé

Application: ELISA

Détail du produit anti-HCRTR1 anticorps

Épitope: N-Term

Réactivité croisée: Humain

Attributs du produit: Ox1r, Hypocretin receptor type 1,As first published in 1998 by Sakurai et al, the initial neuropeptides Orexin A and Orexin B were shown to be important in the regulation of appetite. Continued research now suggests that these peptides also influence a wide range of physiological and behavioral processes such as increased EFG arousal and wakefulness and locomotor activity. In addition to the orexins , two G-protein coupled receptors, designated orexin receptor-1 and orexin receptor-2, have been identified which presumably mediate the signaling events from these neuropeptides1. Recently Orexin Receptors have been found to activate extracellular signal-regulated kinases in CHO cells, namely ERK phosporylation, through Ca2+ influx..2. Further studies seem to indicate a mechanism for orexin receptor mediated cell death and suggest a pathway from GPCRs to apoptosis throughthe MAPK pathways.3

Purification: Antigen Immunoaffiinity Purification

Immunogène: Synthetic peptide made to the N terminal of human Orexin Receptor 1

Isotype: IgG

Information d'application

Indications d'application: Antibody can be used for Western blotting at Optimal concentration should be evaluated by serial dilutions.

Restrictions: For Research Use only

Stockage

Buffer: Immunoaffinity antibody povided as solution in phosphate buffered saline with 0.08 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Détails sur HCRTR1

Antigène: HCRTR1 (Hypocretin (Orexin) Receptor 1 (HCRTR1))

Autre désignation: Orexin Receptor-1

UniProt: O43613

Pathways: Feeding Behaviour