UROD anticorps (N-Term)
Aperçu rapide pour UROD anticorps (N-Term) (ABIN2773790)
Antigène
Voir toutes UROD AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Fonction
- UROD Antibody - N-terminal region
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Séquence
- VPGKGPSFPE PLREEQDLER LRDPEVVASE LGYVFQAITL TRQRLAGRVP
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%, Sheep: 100%, Yeast: 100%, Zebrafish: 83%
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Attributs du produit
- This is a rabbit polyclonal antibody against UROD. It was validated on Western Blot and immunohistochemistry.
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Purification
- Protein A purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human UROD
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8115542
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1.0 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- prevent freeze-thaw cycles
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- UROD (Uroporphyrinogen Decarboxylase (UROD))
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Autre désignation
- UROD
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Sujet
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Background Information: UROD is the fifth enzyme of the heme biosynthetic pathway. This enzyme is responsible for catalyzing the conversion of uroporphyrinogen to coproporphyrinogen through the removal of four carboxymethyl side chains. Mutations and deficiency in this enzyme are known to cause familial porphyria cutanea tarda and hepatoerythropoetic porphyria.This gene encodes the fifth enzyme of the heme biosynthetic pathway. This enzyme is responsible for catalyzing the conversion of uroporphyrinogen to coproporphyrinogen through the removal of four carboxymethyl side chains. Mutations and deficiency in this enzyme are known to cause familial porphyria cutanea tarda and hepatoerythropoetic porphyria.
Gene Name: Uroporphyrinogen decarboxylase
Alternative Symbols: PCT, UPD
Protein Name: Uroporphyrinogen decarboxylase
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Poids moléculaire
- 40kDa
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ID gène
- 7389
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NCBI Accession
- NP_000365
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UniProt
- P06132
Antigène
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