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Ectodysplasin A anticorps (Middle Region)

EDA Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chévre, Cobaye, Cheval, Chien, Lapin, Poisson zèbre (Danio rerio) WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2773846
  • Antigène Voir toutes Ectodysplasin A (EDA) Anticorps
    Ectodysplasin A (EDA)
    Épitope
    • 16
    • 16
    • 9
    • 8
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivité
    • 71
    • 46
    • 27
    • 10
    • 7
    • 6
    • 6
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat, Boeuf (Vache), Chévre, Cobaye, Cheval, Chien, Lapin, Poisson zèbre (Danio rerio)
    Hôte
    • 65
    • 7
    Lapin
    Clonalité
    • 64
    • 7
    • 1
    Polyclonal
    Conjugué
    • 27
    • 5
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Ectodysplasin A est non-conjugé
    Application
    • 67
    • 37
    • 27
    • 26
    • 26
    • 15
    • 11
    • 6
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    GPPGPPGPQG PPGLQGPSGA ADKAGTRENQ PAVVHLQGQG SAIQVKNDLS
    Homologie
    Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
    Attributs du produit
    This is a rabbit polyclonal antibody against EDA. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the middle region of human EDA
    Top Product
    Discover our top product EDA Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 389 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Zhao, Watt, Battle, Li, Bondow, Duncan: "Loss of both GATA4 and GATA6 blocks cardiac myocyte differentiation and results in acardia in mice." dans: Developmental biology, Vol. 317, Issue 2, pp. 614-9, (2008) (PubMed).

  • Antigène
    Ectodysplasin A (EDA)
    Autre désignation
    EDA (EDA Produits)
    Synonymes
    anticorps ECTD1, anticorps ED1, anticorps ED1-A1, anticorps ED1-A2, anticorps EDA-A1, anticorps EDA-A2, anticorps EDA1, anticorps EDA2, anticorps HED, anticorps HED1, anticorps ODT1, anticorps STHAGX1, anticorps XHED, anticorps XLHED, anticorps si:ch73-223d24.5, anticorps Ed1, anticorps Eda-A1, anticorps Eda-A2, anticorps Ta, anticorps tabby, anticorps RGD1563178, anticorps ectodysplasin A, anticorps ectodysplasin-A, anticorps EDA, anticorps eda, anticorps Eda
    Sujet
    EDA is a type II membrane protein that can be cleaved by furin to produce a secreted form. It belongs to the tumor necrosis factor family, acts as a homotrimer and may be involved in cell-cell signaling during the development of ectodermal organs. Defects in this gene are a cause of ectodermal dysplasia, anhidrotic, which is also known as X-linked hypohidrotic ectodermal dysplasia. Several transcript variants encoding many different isoforms have been found for this gene.The protein encoded by this gene is a type II membrane protein that can be cleaved by furin to produce a secreted form. The encoded protein, which belongs to the tumor necrosis factor family, acts as a homotrimer and may be involved in cell-cell signaling during the development of ectodermal organs. Defects in this gene are a cause of ectodermal dysplasia, anhidrotic, which is also known as X-linked hypohidrotic ectodermal dysplasia. Several transcript variants encoding many different isoforms have been found for this gene.
    Alias Symbols: ED1, ED1-A1, ED1-A2, EDA1, EDA2, HED, XHED, XLHED, ODT1, STHAGX1
    Protein Interaction Partner: OSTCP1, OSTC, NIPAL3, GIMAP5, SEC22A, LEPROTL1, DOLK, PLN, MAL, EMP3, CYB561, ATP6V0C, EDAR, EDA, EDA2R, FURIN,
    Protein Size: 389
    Poids moléculaire
    41 kDa
    ID gène
    1896
    NCBI Accession
    NM_001005609, NP_001005609
    UniProt
    Q92838
    Pathways
    Tube Formation
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