NrCAM anticorps (N-Term)
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- Antigène Voir toutes NrCAM (NRCAM) Anticorps
- NrCAM (NRCAM) (Neuronal Cell Adhesion Molecule (NRCAM))
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Épitope
- N-Term
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Reactivité
- Souris, Humain, Rat, Chien, Boeuf (Vache), Cobaye, Cheval, Lapin
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp NrCAM est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Séquence
- NLSDTEFYGA KSSRERPPTF LTPEGNASNK EELRGNVLSL ECIAEGLPTP
- Homologie
- Cow: 86%, Dog: 86%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against NRCAM. It was validated on Western Blot and immunohistochemistry.
- Purification
- Protein A purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human NRCAM
- Top Product
- Discover our top product NRCAM Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 1304 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- NrCAM (NRCAM) (Neuronal Cell Adhesion Molecule (NRCAM))
- Autre désignation
- NRCAM (NRCAM Produits)
- Synonymes
- anticorps CD56, anticorps MSK39, anticorps NCAM, anticorps Bravo, anticorps C030017F07Rik, anticorps C130076O07Rik, anticorps mKIAA0343, anticorps NRCAM, anticorps si:dkey-240a12.1, anticorps Nr-CAM, anticorps neural cell adhesion molecule 1, anticorps neuronal cell adhesion molecule, anticorps neuronal cell adhesion molecule L homeolog, anticorps neuronal cell adhesion molecule a, anticorps NCAM1, anticorps NRCAM, anticorps Nrcam, anticorps nrcam.L, anticorps nrcama, anticorps nrcam
- Sujet
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Cell adhesion molecules (CAMs) are members of the immunoglobulin superfamily. NRCAM is a neuronal cell adhesion molecule with multiple immunoglobulin-like C2-type domains and fibronectin type-III domains. This ankyrin-binding protein is involved in neuron-neuron adhesion and promotes directional signaling during axonal cone growth. NRCAM may also play a general role in cell-cell communication via signaling from its intracellular domain to the actin cytoskeleton during directional cell migration. Allelic variants of its gene have been associated with autism and addiction vulnerability.Cell adhesion molecules (CAMs) are members of the immunoglobulin superfamily. This gene encodes a neuronal cell adhesion molecule with multiple immunoglobulin-like C2-type domains and fibronectin type-III domains. This ankyrin-binding protein is involved in neuron-neuron adhesion and promotes directional signaling during axonal cone growth. This gene is also expressed in non-neural tissues and may play a general role in cell-cell communication via signaling from its intracellular domain to the actin cytoskeleton during directional cell migration. Allelic variants of this gene have been associated with autism and addiction vulnerability. Alternative splicing results in multiple transcript variants encoding different isoforms.
Alias Symbols: KIAA0343, MGC138845, MGC138846
Protein Interaction Partner: LNX1, MAGI3, HSPA12A, MACF1, UBC, NFASC, NRCAM, CNTN2, PTPRB, ANK2,
Protein Size: 1304 - Poids moléculaire
- 141 kDa
- ID gène
- 4897
- NCBI Accession
- NM_001037132, NP_001032209
- UniProt
- Q92823
- Pathways
- Regulation of Cell Size
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