RANBP1 anticorps (C-Term)

N° du produit ABIN2773873

L’anticorps anti-RANBP1 Polyclonal Lapin est utilisé pour la détection de RANBP1 dans des échantillons de Humain, Boeuf (Vache), Cheval et Saccharomyces cerevisiae. Il a été validé pour WB.

Aperçu rapide pour RANBP1 anticorps (C-Term) (ABIN2773873)

Antigène: RANBP1 (RAN Binding Protein 1 (RANBP1))

Reactivité: Humain, Boeuf (Vache), Cheval, Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RANBP1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-RANBP1 anticorps

Épitope: C-Term

Fonction: RANBP1 Antibody - C-terminal region

Séquence: KFEECRKEIE EREKKAGSGK NDHAEKVAEK LEALSVKEET KEDAEEKQ

Homologie: Cow: 79%, Horse: 79%, Human: 100%, Yeast: 90%

Attributs du produit: This is a rabbit polyclonal antibody against RANBP1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human RANBP1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP46083-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur RANBP1

Antigène: RANBP1 (RAN Binding Protein 1 (RANBP1))

Autre désignation: RANBP1

Sujet:

Background Information: Ran/TC4-binding protein, RanBP1, interacts specifically with GTP-charged RAN. RANBP1 encodes a 23-kD protein that binds to RAN complexed with GTP but not GDP. RANBP1 does not activate GTPase activity of RAN but does markedly increase GTP hydrolysis by the RanGTPase-activating protein (RanGAP1). The RANBP1 cDNA encodes a 201-amino acid protein that is 92 % similar to its mouse homolog. In both mammalian cells and in yeast, RANBP1 acts as a negative regulator of RCC1 by inhibiting RCC1-stimulated guanine nucleotide release from RAN.Ran/TC4-binding protein, RanBP1, interacts specifically with GTP-charged RAN. RANBP1 encodes a 23-kD protein that binds to RAN complexed with GTP but not GDP. RANBP1 does not activate GTPase activity of RAN but does markedly increase GTP hydrolysis by the RanGTPase-activating protein (RanGAP1). The RANBP1 cDNA encodes a 201-amino acid protein that is 92 % similar to its mouse homolog. In both mammalian cells and in yeast, RANBP1 acts as a negative regulator of RCC1 by inhibiting RCC1-stimulated guanine nucleotide release from RAN. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Gene Name: RAN binding protein 1

Alternative Symbols: HTF9A

Protein Name: Ran-specific GTPase-activating protein

Poids moléculaire: 23kDa

ID gène: 5902

NCBI Accession: NP_002873

UniProt: P43487