PSMC3IP anticorps (C-Term)

N° du produit ABIN2773902

Cet anticorps anti-PSMC3IP Polyclonal Lapin (ABIN2773902) détecte spécifiquement PSMC3IP dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Chien, Boeuf (Vache), Cheval, Lapin, Chévre, Cobaye, Poisson zèbre (Danio rerio) et Porc.

Aperçu rapide pour PSMC3IP anticorps (C-Term) (ABIN2773902)

Antigène: PSMC3IP (PSMC3 Interacting Protein (PSMC3IP))

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cheval, Lapin, Chévre, Cobaye, Poisson zèbre (Danio rerio), Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PSMC3IP est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PSMC3IP anticorps

Épitope: C-Term

Fonction: PSMC3IP Antibody - C-terminal region

Séquence: PEEKEQVYRE RQKYCKEWRK RKRMATELSD AILEGYPKSK KQFFEEVGIE

Homologie: Cow: 100%, Dog: 100%, Goat: 93%, Guinea Pig: 79%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%

Attributs du produit: This is a rabbit polyclonal antibody against PSMC3IP. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human PSMC3IP

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP47615-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur PSMC3IP

Antigène: PSMC3IP (PSMC3 Interacting Protein (PSMC3IP))

Autre désignation: PSMC3IP

Sujet:

Background Information: PSMC3IP plays an important role in meiotic recombination. It stimulates DMC1-mediated strand exchange required for pairing homologous chromosomes during meiosis. The complex PSMC3IP/MND1 binds DNA, stimulates the recombinase activity of DMC1 as well as DMC1 D-loop formation from double-strand DNA. This complex stabilizes presynaptic RAD51 and DMC1 filaments formed on single strand DNA to capture double-strand DNA. This complex stimulates both synaptic and presynaptic critical steps in RAD51 and DMC1-promoted homologous pairing. It may inhibit HIV-1 viral protein TAT activity and modulate the activity of proteasomes through association with PSMC3.

Gene Name: PSMC3 interacting protein

Alternative Symbols: HOP2, ODG3, GT198, TBPIP, HUMGT198A

Protein Name: Homologous-pairing protein 2 homolog

Poids moléculaire: 24kDa

ID gène: 29893

NCBI Accession: NP_037422

UniProt: Q9P2W1