SEPN1 anticorps (C-Term)

N° du produit ABIN2773903

Détail du produit anti-SEPN1 anticorps

Antigène: SEPN1 (Selenoprotein N, 1 (SEPN1))

Épitope: C-Term

Reactivité: Humain, Souris, Boeuf (Vache), Cobaye, Cheval, Rat, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SEPN1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: ANYFLDITSV KPEEIESNLF SFSSTFEDPS TATYMQFLKE GLRRGLPLLQ

Homologie: Cow: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rat: 100%, Zebrafish: 79%

Attributs du produit: This is a rabbit polyclonal antibody against SEPN1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human SEPN1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 590 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur SEPN1

Antigène: SEPN1 (Selenoprotein N, 1 (SEPN1))

Autre désignation: SEPN1 (SEPN1 Produits)

Synonymes: anticorps CFTD, anticorps MDRS1, anticorps RSMD1, anticorps RSS, anticorps SELN, anticorps 1110019I12Rik, anticorps AI414492, anticorps SePN, anticorps cb686, anticorps wu:fb06g01, anticorps wu:fb73d02, anticorps wu:fv41b08, anticorps zgc:101091, anticorps selenoprotein N, anticorps SELENON, anticorps Selenon, anticorps selenon

Sujet: SEPN1 is a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. Mutations in SEPN1 gene cause the classical phenotype of multiminicore disease and congenital muscular dystrophy with spinal rigidity and restrictive respiratory syndrome. This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Mutations in this gene cause the classical phenotype of multiminicore disease and congenital muscular dystrophy with spinal rigidity and restrictive respiratory syndrome. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Alias Symbols: FLJ24021, MDRS1, RSMD1, RSS, SELN, CFTD
Protein Interaction Partner: ELAVL1, UBC,
Protein Size: 590

Poids moléculaire: 62 kDa

ID gène: 57190

NCBI Accession: NM_020451, NP_065184

UniProt: Q9NZV5

Pathways: Skeletal Muscle Fiber Development