ST14 anticorps (C-Term)

N° du produit ABIN2773910

Cité dans 1 publication. Cet anticorps anti-ST14 Polyclonal Lapin (ABIN2773910) détecte spécifiquement ST14 dans WB et IHC. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Boeuf (Vache), Cobaye, Cheval, Chien, Porc et Lapin.

Aperçu rapide pour ST14 anticorps (C-Term) (ABIN2773910)

Antigène: ST14 (Suppression of Tumorigenicity 14 (ST14))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cobaye, Cheval, Chien, Porc, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ST14 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-ST14 anticorps

Épitope: C-Term

Fonction: ST14 Antibody - C-terminal region

Séquence: SHVFPAGKAI WVTGWGHTQY GGTGALILQK GEIRVINQTT CENLLPQQIT

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against ST14. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human ST14

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8113083

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-ST14 (ABIN2773910)

Landova Sulcova, Zahradnicek, Dumkova, Dosedelova, Krivanek, Hampl, Kavkova, Zikmund, Gregorovicova, Sedmera, Kaiser, Tucker, Buchtova: "Developmental mechanisms driving complex tooth shape in reptiles." dans: Developmental dynamics : an official publication of the American Association of Anatomists, Vol. 249, Issue 4, pp. 441-464, (2020) (PubMed).

Détails sur ST14

Antigène: ST14 (Suppression of Tumorigenicity 14 (ST14))

Autre désignation: ST14

Sujet:

Background Information: ST14 is an epithelial-derived, integral membrane serine protease. This protease forms a complex with the Kunitz-type serine protease inhibitor, HAI-1, and is found to be activated by sphingosine 1-phosphate. This protease has been shown to cleave and activate hepatocyte growth factor/scattering factor, and urokinase plasminogen activator, which suggest the function of this protease as an epithelial membrane activator for other proteases and latent growth factors. The expression of this protease has been associated with breast, colon, prostate, and ovarian tumors, which implicates its role in cancer invasion, and metastasis.

Gene Name: Suppression of tumorigenicity 14 (colon carcinoma)

Alternative Symbols: HAI, CAP3, MTSP1, SNC19, ARCI11, MT-SP1, PRSS14, TADG15, TMPRSS14

Protein Name: Suppressor of tumorigenicity 14 protein

Poids moléculaire: 95kDa

ID gène: 6768

UniProt: Q9Y5Y6