PCMT1 anticorps (Middle Region)
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- Antigène Voir toutes PCMT1 Anticorps
- PCMT1 (Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase (PCMT1))
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Épitope
- Middle Region
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Reactivité
- Humain, Souris, Rat, Lapin, Boeuf (Vache), Chien, Cobaye, Poisson zèbre (Danio rerio), Chévre, Cheval
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PCMT1 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- APYDAIHVGA AAPVVPQALI DQLKPGGRLI LPVGPAGGNQ MLEQYDKLQD
- Homologie
- Cow: 100%, Dog: 100%, Goat: 79%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
- Attributs du produit
- This is a rabbit polyclonal antibody against PCMT1. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Protein A purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human PCMT1
- Top Product
- Discover our top product PCMT1 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 227 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- PCMT1 (Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase (PCMT1))
- Autre désignation
- PCMT1 (PCMT1 Produits)
- Synonymes
- anticorps PIMT, anticorps C79501, anticorps PCM, anticorps PCMT, anticorps etID309741.20, anticorps fj13d06, anticorps pimt, anticorps wu:fj13d06, anticorps protein-L-isoaspartate (D-aspartate) O-methyltransferase, anticorps protein-L-isoaspartate (D-aspartate) O-methyltransferase 1, anticorps protein-L-isoaspartate (D-aspartate) O-methyltransferase L homeolog, anticorps protein-L-isoaspartate(D-aspartate)O-methyltransferase, anticorps PCMT1, anticorps Pcmt1, anticorps pcmt1.L, anticorps pcmt1, anticorps pcmt
- Sujet
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Three classes of protein carboxyl methyltransferases, distinguished by their methyl-acceptor substrate specificity, have been found in prokaryotic and eukaryotic cells. The type II enzyme catalyzes the transfer of a methyl group from S-adenosyl-L-methionine to the free carboxyl groups of D-aspartyl and L-isoaspartyl residues. These methyl-accepting residues result from the spontaneous deamidation, isomerization, and racemization of normal L-aspartyl and L-asparaginyl residues and represent sites of covalent damage to aging proteins PCMT1 (EC 2.1.1.77) is a protein repair enzyme that initiates the conversion of abnormal D-aspartyl and L-isoaspartyl residues to the normal L-aspartyl form.Three classes of protein carboxyl methyltransferases, distinguished by their methyl-acceptor substrate specificity, have been found in prokaryotic and eukaryotic cells. The type II enzyme catalyzes the transfer of a methyl group from S-adenosyl-L-methionine to the free carboxyl groups of D-aspartyl and L-isoaspartyl residues. These methyl-accepting residues result from the spontaneous deamidation, isomerization, and racemization of normal L-aspartyl and L-asparaginyl residues and represent sites of covalent damage to aging proteins PCMT1 (EC 2.1.1.77) is a protein repair enzyme that initiates the conversion of abnormal D-aspartyl and L-isoaspartyl residues to the normal L-aspartyl form.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: PIMT
Protein Interaction Partner: RPIA, HUWE1, AIMP2, TP53, AURKA, UBC, SUMO1, NEDD8, SH3RF2, LMNA, VCAM1, ITGA4, FN1, CFTR, VKORC1, TP53BP1, SDHAF2, NANS, UBE2C, SEC24A, PPIH, ZRANB2, UCHL3, TPM4, SVIL, RRM2, RAD23A, PSMB7, PFDN2, NOTCH2, GDI1, ATP6V1B2, APOE, CUL1, CUL2, CUL3, CDK2, CAN
Protein Size: 227 - Poids moléculaire
- 25 kDa
- ID gène
- 5110
- NCBI Accession
- NM_005389, NP_005380
- UniProt
- P22061
- Pathways
- Ribonucleoprotein Complex Subunit Organization
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