PRTFDC1 anticorps (Middle Region)

N° du produit ABIN2773930

L’anticorps Lapin Polyclonal anti-PRTFDC1 a été validé pour WB. Il convient pour détecter PRTFDC1 dans des échantillons de Humain, Rat, Porc, Cheval, Lapin, Chien et Poisson zèbre (Danio rerio). Il y a 1 publication disponible.

Aperçu rapide pour PRTFDC1 anticorps (Middle Region) (ABIN2773930)

Antigène: PRTFDC1 (phosphoribosyl Transferase Domain Containing 1 (PRTFDC1))

Reactivité: Humain, Rat, Porc, Cheval, Lapin, Chien, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PRTFDC1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PRTFDC1 anticorps

Épitope: Middle Region

Séquence: MKALLSNIEK YKPNMIKVAS LLVKRTSRSD GFRPDYAGFE IPNLFVVGYA

Homologie: Dog: 92%, Horse: 100%, Human: 100%, Pig: 100%, Rabbit: 77%, Rat: 92%, Zebrafish: 77%

Attributs du produit: This is a rabbit polyclonal antibody against PRTFDC1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human PRTFDC1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 225 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-PRTFDC1 (ABIN2773930)

Suzuki, Imoto, Pimkhaokham, Nakagawa, Kamata, Kozaki, Amagasa, Inazawa: "PRTFDC1, a possible tumor-suppressor gene, is frequently silenced in oral squamous-cell carcinomas by aberrant promoter hypermethylation." dans: Oncogene, Vol. 26, Issue 57, pp. 7921-32, (2007) (PubMed).

Détails sur PRTFDC1

Antigène: PRTFDC1 (phosphoribosyl Transferase Domain Containing 1 (PRTFDC1))

Autre désignation: PRTFDC1

Sujet: PRTFDC1 belongs to the purine/pyrimidine phosphoribosyltransferase family. Epigenetic silencing of PRTFDC1 by hypermethylation of the CpG islands leads to a loss of PRTFDC1 function, which might be involved in squamous cell oral carcinogenesis.
Alias Symbols: FLJ11888, HHGP
Protein Interaction Partner: LGALS9B, EEF2KMT, MCMBP, GNPDA1, EPM2AIP1, TCL1A, HPRT1, UBC, RTN3, FLAD1, NIF3L1, DTNB, STAT5A, EWSR1,
Protein Size: 225

Poids moléculaire: 26 kDa

ID gène: 56952

NCBI Accession: NM_020200, NP_064585

UniProt: Q9NRG1

Pathways: Ribonucleoside Biosynthetic Process