MYCNOS anticorps (N-Term)

N° du produit ABIN2773988

Détail du produit anti-MYCNOS anticorps

Antigène: MYCNOS (MYCN Opposite Strand/antisense RNA (MYCNOS))

Épitope: N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MYCNOS est non-conjugé

Application: Western Blotting (WB)

Séquence: WGGETDASNP APALTACCAA EREANVEQGL AGRLLLCNYE RRLVRRCKIA

Homologie: Human: 100%

Attributs du produit: This is a rabbit polyclonal antibody against MYCNOS. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 109 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur MYCNOS

Antigène: MYCNOS (MYCN Opposite Strand/antisense RNA (MYCNOS))

Autre désignation: MYCNOS (MYCNOS Produits)

Synonymes: anticorps MYCN-AS1, anticorps NCYM, anticorps NYCM, anticorps MYCN opposite strand, anticorps MYCNOS

Sujet: The N-myc oncogene has been implicated in the pathogenesis of a number of human tumors, including childhood neuroblastoma and adult small cell lung cancer. Complementary DNA clones derived from a transcription unit, N-cym, located on the opposite DNA strand to N-myc have been characterized. There is extensive overlap between the 5' ends of the two transcription units. The N-cym gene, which can encode a 109-amino acid protein, is expressed during fetal development, as well as in tumor cell lines containing amplified N-myc loci, where it is expressed at very high levels. Although other examples of overlapping, opposite-strand eukaryotic genes exist, N-myc and N-cym are unique in that they appear to be coregulated in tumor cell lines under basal growth conditions and in response to the differentiating agent retinoic acid. This coregulation suggests that their protein products may be functionally interrelated during normal development and oncogenesis.
Alias Symbols: NCYM, NYCM, MYCN-AS1
Protein Size: 109

Poids moléculaire: 12 kDa

ID gène: 10408

NCBI Accession: NM_006316, NP_006307

UniProt: P40205