FRS3 anticorps (Middle Region)

N° du produit ABIN2774008

Détail du produit anti-FRS3 anticorps

Antigène: FRS3 (Fibroblast Growth Factor Receptor Substrate 3 (FRS3))

Épitope: Middle Region

Reactivité: Humain, Rat, Souris, Lapin, Chien, Cheval, Boeuf (Vache), Cobaye, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FRS3 est non-conjugé

Application: Western Blotting (WB)

Séquence: GFPDGEEDET PLQKPTSTRA AIRSHGSFPV PLTRRRGSPR VFNFDFRRPG

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against FRS3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human FRS3

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 492 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur FRS3

Antigène: FRS3 (Fibroblast Growth Factor Receptor Substrate 3 (FRS3))

Autre désignation: FRS3 (FRS3 Produits)

Synonymes: anticorps MGC82242, anticorps snt2, anticorps frs2b, anticorps snt-2, anticorps frs2beta, anticorps FRS2-beta, anticorps FRS2B, anticorps FRS2beta, anticorps SNT-2, anticorps SNT2, anticorps 4930417B13Rik, anticorps AI449674, anticorps Frs2beta, anticorps Snt2, anticorps fibroblast growth factor receptor substrate 3 S homeolog, anticorps fibroblast growth factor receptor substrate 3, anticorps frs3.S, anticorps FRS3, anticorps frs3, anticorps Frs3

Sujet: FRS3 is an adapter protein that links FGR and NGF receptors to downstream signaling pathways. FRS3 is involved in the activation of MAP kinases. FRS3 down-regulates ERK2 signaling by interfering with the phosphorylation and nuclear translocation of ERK2.The protein encoded by this gene is a substrate for the fibroblast growth factor receptor. It is found in peripheral plasma membrane and functions in linking FGF receptor stimulation to activators of Ras. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: FRS2B, FRS2beta, MGC17167, SNT-2, SNT2
Protein Interaction Partner: NOTCH2NL, RFX6, SPERT, ADAMTSL4, SH3KBP1, CD2AP, SPRY2, TRIP6, TCF4, PLSCR1, GATA1, ERBB2, CBL, AES, ELAVL1, RND1, KARS, BMPR2, NTRK2, PRKCI, NTRK1, MAPK1, PTPN11, FGFR1, GRB2,
Protein Size: 492

Poids moléculaire: 54 kDa

ID gène: 10817

NCBI Accession: NM_006653, NP_006644

UniProt: O43559