WARS2 anticorps (Middle Region)

N° du produit ABIN2774013

Cité dans 1 publication. Cet anticorps anti-WARS2 Polyclonal Lapin (ABIN2774013) détecte spécifiquement WARS2 dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin, Saccharomyces cerevisiae et Poisson zèbre (Danio rerio).

Aperçu rapide pour WARS2 anticorps (Middle Region) (ABIN2774013)

Antigène: WARS2 (Tryptophanyl tRNA Synthetase 2, Mitochondrial (WARS2))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin, Saccharomyces cerevisiae, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp WARS2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-WARS2 anticorps

Épitope: Middle Region

Fonction: WARS2 Antibody - middle region

Séquence: TTKQKHDGTV GLLTYPVLQA ADILLYKSTH VPVGEDQVQH MELVQDLAQG

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 93%, Zebrafish: 93%

Attributs du produit: This is a rabbit polyclonal antibody against WARS2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human WARS2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8114844

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-WARS2 (ABIN2774013)

Wang, Sips, Khin, Rotival, Sun, Ahmed, Widjaja, Schafer, Yusoff, Choksi, Ko, Singh, Epstein, Guan, Houštěk, Mracek, Nuskova, Mikell, Tan, Pesce, Kolar, Bottolo, Mancini, Hubner, Pravenec, Petretto et al.: "Wars2 is a determinant of angiogenesis. ..." dans: Nature communications, Vol. 7, pp. 12061, (2016) (PubMed).

Détails sur WARS2

Antigène: WARS2 (Tryptophanyl tRNA Synthetase 2, Mitochondrial (WARS2))

Autre désignation: WARS2

Sujet:

Background Information: Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Two forms of tryptophanyl-tRNA synthetase exist, a cytoplasmic form, named WARS, and a mitochondrial form, named WARS2. WARS2 is the mitochondrial tryptophanyl-tRNA synthetase. Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Two forms of tryptophanyl-tRNA synthetase exist, a cytoplasmic form, named WARS, and a mitochondrial form, named WARS2. This gene encodes the mitochondrial tryptophanyl-tRNA synthetase. Two alternative transcripts encoding different isoforms have been described.

Gene Name: Tryptophanyl tRNA synthetase 2, mitochondrial

Alternative Symbols: TrpRS, NEMMLAS, mtTrpRS

Protein Name: Tryptophan--tRNA ligase, mitochondrial

Poids moléculaire: 24kDa

ID gène: 10352

NCBI Accession: NP_957715

UniProt: Q9UGM6