CRYGC anticorps (Middle Region)

N° du produit ABIN2774014

Cet anticorps anti-CRYGC Polyclonal Lapin (ABIN2774014) détecte spécifiquement CRYGC dans WB. L’anticorps est réactif avec des échantillons de Humain, Rat, Lapin, Boeuf (Vache), Chien et Cheval.

Aperçu rapide pour CRYGC anticorps (Middle Region) (ABIN2774014)

Antigène: CRYGC (Crystallin, gamma C (CRYGC))

Reactivité: Humain, Rat, Lapin, Boeuf (Vache), Chien, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CRYGC est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CRYGC anticorps

Épitope: Middle Region

Fonction: CRYGC Antibody - middle region

Séquence: GLSDSIRSCC LIPQTVSHRL RLYEREDHKG LMMELSEDCP SIQDRFHLSE

Homologie: Cow: 79%, Dog: 93%, Horse: 86%, Human: 100%, Rabbit: 86%, Rat: 79%

Attributs du produit: This is a rabbit polyclonal antibody against CRYGC. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human CRYGC

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP52388-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur CRYGC

Antigène: CRYGC (Crystallin, gamma C (CRYGC))

Autre désignation: CRYGC

Sujet:

Background Information: Crystallins are the dominant structural components of the vertebrate eye lens.Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families, beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Gamma-crystallins are a homogeneous group of highly symmetrical, monomeric proteins typically lacking connecting peptides and terminal extensions. They are differentially regulated after early development. Four gamma-crystallin genes (gamma-A through gamma-D) and three pseudogenes (gamma-E, gamma-F, gamma-G) are tandemly organized in a genomic segment as a gene cluster. Whether due to aging or mutations in specific genes, gamma-crystallins have been involved in cataract formation. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Gene Name: Crystallin, gamma C

Alternative Symbols: CCL, CRYG3, CTRCT2

Protein Name: Gamma-crystallin C

Poids moléculaire: 21kDa

ID gène: 1420

NCBI Accession: NP_066269

UniProt: P07315