ATG12 anticorps (Middle Region)
Aperçu rapide pour ATG12 anticorps (Middle Region) (ABIN2774065)
Antigène
Voir toutes ATG12 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Middle Region
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Séquence
- KFLKLVASEQ LFIYVNQSFA PSPDQEVGTL YECFGSDGKL VLHYCKSQAW
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 100%
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Attributs du produit
- This is a rabbit polyclonal antibody against ATG12. It was validated on Western Blot.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human ATG12
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 187 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- ATG12 (Autophagy Related 12 (ATG12))
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Autre désignation
- ATG12
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Sujet
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Autophagy is a process of bulk protein degradation in which cytoplasmic components, including organelles, are enclosed in double-membrane structures called autophagosomes and delivered to lysosomes or vacuoles for degradation. ATG12 is the human homolog of a yeast protein involved in autophagy (Mizushima et al., 1998 [PubMed 9852036]).
Alias Symbols: APG12, APG12L, FBR93, HAPG12
Protein Interaction Partner: CRX, WIPI2, FADD, EXOC4, Atg10, ATG3, ATG5, CAV1, ATG16L1, WDFY3, APP, BCL2, MCL1, TECPR1, UBC, ATG7, ATG4B, GABARAP, MAP1B, KRTAP4-12, PLSCR1, MDFI, PTK2, DHX36, OTUD4, SF3B1, SF3A1, AUP1,
Protein Size: 187 -
Poids moléculaire
- 21 kDa
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ID gène
- 9140
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NCBI Accession
- NM_004707, NP_004698
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UniProt
- O94817
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Pathways
- Autophagy
Antigène
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