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CHMP2B anticorps (N-Term)

CHMP2B Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Porc, Lapin, Cobaye, Poisson zèbre (Danio rerio) WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2774093
  • Antigène Voir toutes CHMP2B Anticorps
    CHMP2B (Charged Multivesicular Body Protein 2B (CHMP2B))
    Épitope
    • 15
    • 14
    • 8
    • 5
    • 3
    • 2
    • 1
    • 1
    N-Term
    Reactivité
    Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Porc, Lapin, Cobaye, Poisson zèbre (Danio rerio)
    Hôte
    • 51
    • 3
    • 2
    Lapin
    Clonalité
    • 52
    • 4
    Polyclonal
    Conjugué
    • 25
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CHMP2B est non-conjugé
    Application
    • 45
    • 21
    • 20
    • 14
    • 13
    • 7
    • 7
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    ASLFKKKTVD DVIKEQNREL RGTQRAIIRD RAALEKQEKQ LELEIKKMAK
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
    Attributs du produit
    This is a rabbit polyclonal antibody against Chmp2b. It was validated on Western Blot.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the N-terminal region of Rat Chmp2b
    Top Product
    Discover our top product CHMP2B Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 213 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    CHMP2B (Charged Multivesicular Body Protein 2B (CHMP2B))
    Autre désignation
    Chmp2b (CHMP2B Produits)
    Synonymes
    anticorps ALS17, anticorps CHMP2.5, anticorps DMT1, anticorps VPS2-2, anticorps VPS2B, anticorps 1190006E07Rik, anticorps RGD1306781, anticorps chmp2b, anticorps chmp2bl, anticorps zgc:77025, anticorps si:ch211-224m9.5, anticorps CHMP2B, anticorps cg4618, anticorps chmp2.5, anticorps dmt1, anticorps vps2-2, anticorps vps2b, anticorps CHMP2b-B, anticorps chmp2b-a, anticorps chmp2b-b, anticorps charged multivesicular body protein 2B, anticorps charged multivesicular body protein 2Bb, anticorps charged multivesicular body protein 2Ba, anticorps charged multivesicular body protein 2B pseudogene, anticorps charged multivesicular body protein 2B S homeolog, anticorps charged multivesicular body protein 2B L homeolog, anticorps CHMP2B, anticorps Chmp2b, anticorps chmp2bb, anticorps chmp2ba, anticorps LOC747711, anticorps chmp2b.S, anticorps chmp2b.L
    Sujet
    Chmp2b is involved in late steps of the endosomal multivesicular bodies (MVB) pathway. Chmp2b recognizes membrane-associated ESCRT-III assemblies and catalyzes their disassembly, possibly in combination with membrane fission. Chmp2b redistributes the ESCRT-III components to the cytoplasm for further rounds of MVB sorting. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. In conjunction with the ESCRT machinery Chmp2b also appears to function in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis. Involved in cytokinesis .
    Alias Symbols: RGD1306781
    Protein Size: 213
    Poids moléculaire
    23 kDa
    ID gène
    363720
    NCBI Accession
    XM_001063932, XP_001063932
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