CHMP2B anticorps (N-Term)
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- Antigène Voir toutes CHMP2B Anticorps
- CHMP2B (Charged Multivesicular Body Protein 2B (CHMP2B))
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Épitope
- N-Term
- Reactivité
- Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Porc, Lapin, Cobaye, Poisson zèbre (Danio rerio)
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp CHMP2B est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- ASLFKKKTVD DVIKEQNREL RGTQRAIIRD RAALEKQEKQ LELEIKKMAK
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
- Attributs du produit
- This is a rabbit polyclonal antibody against Chmp2b. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the N-terminal region of Rat Chmp2b
- Top Product
- Discover our top product CHMP2B Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 213 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- CHMP2B (Charged Multivesicular Body Protein 2B (CHMP2B))
- Autre désignation
- Chmp2b (CHMP2B Produits)
- Synonymes
- anticorps ALS17, anticorps CHMP2.5, anticorps DMT1, anticorps VPS2-2, anticorps VPS2B, anticorps 1190006E07Rik, anticorps RGD1306781, anticorps chmp2b, anticorps chmp2bl, anticorps zgc:77025, anticorps si:ch211-224m9.5, anticorps CHMP2B, anticorps cg4618, anticorps chmp2.5, anticorps dmt1, anticorps vps2-2, anticorps vps2b, anticorps CHMP2b-B, anticorps chmp2b-a, anticorps chmp2b-b, anticorps charged multivesicular body protein 2B, anticorps charged multivesicular body protein 2Bb, anticorps charged multivesicular body protein 2Ba, anticorps charged multivesicular body protein 2B pseudogene, anticorps charged multivesicular body protein 2B S homeolog, anticorps charged multivesicular body protein 2B L homeolog, anticorps CHMP2B, anticorps Chmp2b, anticorps chmp2bb, anticorps chmp2ba, anticorps LOC747711, anticorps chmp2b.S, anticorps chmp2b.L
- Sujet
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Chmp2b is involved in late steps of the endosomal multivesicular bodies (MVB) pathway. Chmp2b recognizes membrane-associated ESCRT-III assemblies and catalyzes their disassembly, possibly in combination with membrane fission. Chmp2b redistributes the ESCRT-III components to the cytoplasm for further rounds of MVB sorting. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. In conjunction with the ESCRT machinery Chmp2b also appears to function in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis. Involved in cytokinesis .
Alias Symbols: RGD1306781
Protein Size: 213 - Poids moléculaire
- 23 kDa
- ID gène
- 363720
- NCBI Accession
- XM_001063932, XP_001063932
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