HTRA4 anticorps (Middle Region)
Aperçu rapide pour HTRA4 anticorps (Middle Region) (ABIN2774114)
Antigène
Voir toutes HTRA4 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Middle Region
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Séquence
- LKMHYPDFPD VSSGVYVCKV VEGTAAQSSG LRDHDVIVNI NGKPITTTTD
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Homologie
- Cow: 86%, Dog: 93%, Guinea Pig: 86%, Horse: 92%, Human: 100%, Mouse: 86%, Pig: 93%, Rabbit: 93%, Rat: 93%
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Attributs du produit
- This is a rabbit polyclonal antibody against HTRA4. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human HTRA4
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 476 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- HTRA4 (HtrA Serine Peptidase 4 (HTRA4))
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Autre désignation
- HTRA4
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Sujet
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HTRA4 is a member of the HtrA family of proteases. The protein contains a putative signal peptide, an insulin growth factor binding domain, a Kazal protease inhibitor domain, a conserved trypsin domain and a PDZ domain. Based on studies on other related family members, this enzyme may function as a secreted oligomeric chaperone protease to degrade misfolded secretory proteins. Other human HtrA proteins have been implicated in arthritis, tumor suppression, unfolded stress response, apoptosis, and aging.
Alias Symbols: FLJ90724
Protein Size: 476 -
Poids moléculaire
- 51 kDa
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ID gène
- 203100
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NCBI Accession
- NM_153692, NP_710159
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UniProt
- P83105
Antigène
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