Acylglycerol Kinase anticorps (N-Term)

N° du produit ABIN2774178

Cet anticorps Lapin Polyclonal détecte spécifiquement Acylglycerol Kinase dans WB. Il présente une réactivité envers Humain, Souris, Rat, Chien, Cobaye, Lapin, Boeuf (Vache) et Cheval.

Aperçu rapide pour Acylglycerol Kinase anticorps (N-Term) (ABIN2774178)

Antigène: Acylglycerol Kinase (AGK)

Reactivité: Humain, Souris, Rat, Chien, Cobaye, Lapin, Boeuf (Vache), Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Acylglycerol Kinase est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Acylglycerol Kinase anticorps

Épitope: N-Term

Séquence: KKLLELMENT DVIIVAGGDG TLQEVVTGVL RRTDEATFSK IPIGFIPLGE

Homologie: Cow: 93%, Dog: 86%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against AGK. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human AGK

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 422 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Acylglycerol Kinase

Antigène: Acylglycerol Kinase (AGK)

Autre désignation: AGK

Sujet: AGK is a lipid kinase that can phosphorylate both monoacylglycerol and diacylglycerol to form lysophosphatidic acid (LPA) and phosphatidic acid (PA), respectively. AGK does not phosphorylate sphingosine. Overexpression of AGK increases the formation and secretion of LPA, resulting in transactivation of EGFR and activation of the downstream MAPK signaling pathway, leading to increased cell growth.
Alias Symbols: FLJ10842, MULK, MTDPS10
Protein Interaction Partner: PCSK9, UBC, RNF2, BMI1, PARK2, FBXO6, UBD, CUL3, AGO4, RYK, ICT1, SNX4, PDLIM1, HCK,
Protein Size: 422

Poids moléculaire: 47 kDa

ID gène: 55750

NCBI Accession: NM_018238, NP_060708

UniProt: Q53H12