Acylglycerol Kinase anticorps (N-Term)
Aperçu rapide pour Acylglycerol Kinase anticorps (N-Term) (ABIN2774178)
Antigène
Voir toutes Acylglycerol Kinase (AGK) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Fonction
- AGK Antibody - N-terminal region
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Séquence
- KKLLELMENT DVIIVAGGDG TLQEVVTGVL RRTDEATFSK IPIGFIPLGE
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Homologie
- Cow: 93%, Dog: 86%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%
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Attributs du produit
- This is a rabbit polyclonal antibody against AGK. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human AGK
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP57170-100UG
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- prevent freeze-thaw cycles
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- Acylglycerol Kinase (AGK)
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Autre désignation
- AGK
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Sujet
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Background Information: AGK is a lipid kinase that can phosphorylate both monoacylglycerol and diacylglycerol to form lysophosphatidic acid (LPA) and phosphatidic acid (PA), respectively. AGK does not phosphorylate sphingosine. Overexpression of AGK increases the formation and secretion of LPA, resulting in transactivation of EGFR and activation of the downstream MAPK signaling pathway, leading to increased cell growth.
Gene Name: Acylglycerol kinase
Alternative Symbols: MULK, CATC5, CTRCT38, MTDPS10
Protein Name: Acylglycerol kinase, mitochondrial
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Poids moléculaire
- 47kDa
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ID gène
- 55750
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NCBI Accession
- NP_060708
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UniProt
- Q53H12
Antigène
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