RNF216 anticorps (N-Term)

N° du produit ABIN2774202

Cet anticorps Lapin Polyclonal détecte spécifiquement RNF216 dans WB. Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Boeuf (Vache), Cheval, Chien, Cobaye et Lapin.

Aperçu rapide pour RNF216 anticorps (N-Term) (ABIN2774202)

Antigène: RNF216 (Ring Finger Protein 216 (RNF216))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cheval, Chien, Cobaye, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RNF216 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-RNF216 anticorps

Épitope: N-Term

Fonction: Rnf216 Antibody - N-terminal region

Séquence: IVNPRLEQKV IILGENGLLF PESEPLEVQN QSSEDSETEL LSNPGEPAAS

Homologie: Cow: 86%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against Rnf216. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of MOUSE Rnf216

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP57824-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur RNF216

Antigène: RNF216 (Ring Finger Protein 216 (RNF216))

Autre désignation: Rnf216

Sujet:

Background Information: Rnf216 acts as an E3 ubiquitin ligase, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and then transfers it to substrates promoting their degradation by the proteasome. It promotes degradation of TRAF3, TLR4 and TLR9. It contributes to the regulation of antiviral responses. It down-regulates activation of NF-kappa-B, IRF3 activation and IFNB production and promotes TNF and RIP mediated apoptosis.

Gene Name: ring finger protein 216

Alternative Symbols: UIP, UIP83, C86502, TRIAD3, Ubce7i, AI647468, AU019462, Ubce7ip1, 2810055G22Rik, F830018F18Rik

Protein Name: E3 ubiquitin-protein ligase RNF216

Poids moléculaire: 93kDa

ID gène: 108086

UniProt: P58283