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RNF216 anticorps (N-Term)

RNF216 Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cheval, Chien, Cobaye, Lapin WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2774202
  • Antigène Voir toutes RNF216 Anticorps
    RNF216 (Ring Finger Protein 216 (RNF216))
    Épitope
    • 9
    • 8
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 43
    • 31
    • 18
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat, Boeuf (Vache), Cheval, Chien, Cobaye, Lapin
    Hôte
    • 44
    Lapin
    Clonalité
    • 44
    Polyclonal
    Conjugué
    • 20
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp RNF216 est non-conjugé
    Application
    • 22
    • 14
    • 14
    • 13
    • 9
    • 7
    • 2
    • 1
    Western Blotting (WB)
    Séquence
    IVNPRLEQKV IILGENGLLF PESEPLEVQN QSSEDSETEL LSNPGEPAAS
    Homologie
    Cow: 86%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 93%
    Attributs du produit
    This is a rabbit polyclonal antibody against Rnf216. It was validated on Western Blot.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the N-terminal region of MOUSE Rnf216
    Top Product
    Discover our top product RNF216 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeat freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    RNF216 (Ring Finger Protein 216 (RNF216))
    Autre désignation
    Rnf216 (RNF216 Produits)
    Synonymes
    anticorps RGD1565135, anticorps TRIAD3, anticorps RNF216, anticorps zin, anticorps u7i1, anticorps triad3, anticorps ubce7ip1, anticorps MGC147026, anticorps 2810055g22rik, anticorps 2810055G22Rik, anticorps AI647468, anticorps AU019462, anticorps C86502, anticorps F830018F18Rik, anticorps UIP83, anticorps Ubce7ip1, anticorps CAHH, anticorps U7I1, anticorps UBCE7IP1, anticorps ZIN, anticorps ring finger protein 216, anticorps Rnf216, anticorps RNF216, anticorps rnf216
    Sujet
    Rnf216 acts as an E3 ubiquitin ligase, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and then transfers it to substrates promoting their degradation by the proteasome. It promotes degradation of TRAF3, TLR4 and TLR9. It contributes to the regulation of antiviral responses. It down-regulates activation of NF-kappa-B, IRF3 activation and IFNB production and promotes TNF and RIP mediated apoptosis.
    Protein Interaction Partner: Ube2l3,
    Protein Size: 853
    Poids moléculaire
    93 kDa
    ID gène
    108086
    UniProt
    P58283
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