Homeobox A11 anticorps (Middle Region)
Aperçu rapide pour Homeobox A11 anticorps (Middle Region) (ABIN406665)
Antigène
Voir toutes Homeobox A11 (HOXA11) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Middle Region
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Séquence
- FETAYGTPEN LASSDYPGDK SAEKGPPAAT ATSAAAAAAA TGAPATSSSD
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Homologie
- Cow: 100%, Dog: 93%, Horse: 100%, Human: 100%, Mouse: 86%, Pig: 86%, Rabbit: 100%, Rat: 92%
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Attributs du produit
- This is a rabbit polyclonal antibody against HOXA11. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human HOXA11
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 313 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Homeobox A11 (HOXA11)
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Autre désignation
- HOXA11
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Sujet
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In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. HOXA11 gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. This gene is involved in the regulation of uterine development and is required for female fertility. Mutations in this gene can cause radio-ulnar synostosis with amegakaryocytic thrombocytopenia.In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. This gene is involved in the regulation of uterine development and is required for female fertility. Mutations in this gene can cause radio-ulnar synostosis with amegakaryocytic thrombocytopenia. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: HOX1, HOX1I
Protein Interaction Partner: PGBD3, UBC, YY1, HDAC2, HDAC1, FOXO1, GMNN, MEIS1, CREBBP,
Protein Size: 313 -
Poids moléculaire
- 34 kDa
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ID gène
- 3207
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NCBI Accession
- NM_005523, NP_005514
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UniProt
- P31270
Antigène
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