UBA1 anticorps (N-Term)

N° du produit ABIN2774233

L’anticorps Lapin Polyclonal anti-UBA1 a été validé pour WB. Il convient pour détecter UBA1 dans des échantillons de Humain, Rat, Souris, Chien, Boeuf (Vache), Cheval, Lapin et Cobaye. Il y a 1 publication disponible.

Aperçu rapide pour UBA1 anticorps (N-Term) (ABIN2774233)

Antigène: UBA1 (Ubiquitin-Like Modifier Activating Enzyme 1 (UBA1))

Reactivité: Humain, Rat, Souris, Chien, Boeuf (Vache), Cheval, Lapin, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UBA1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-UBA1 anticorps

Épitope: N-Term

Séquence: MEAGPPGSAR PAEPGPCLSG QRGADHTASA SLQSVAGTEP GRHPQAVAAV

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against UBA1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human UBA1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 1058 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-UBA1 (ABIN2774233)

Rogers, Olivier, Meyerholz, Dupuy: "Adaptive immunity does not strongly suppress spontaneous tumors in a Sleeping Beauty model of cancer." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 190, Issue 8, pp. 4393-9, (2013) (PubMed).

Détails sur UBA1

Antigène: UBA1 (Ubiquitin-Like Modifier Activating Enzyme 1 (UBA1))

Autre désignation: UBA1

Sujet: UBA1 activates ubiquitin by first adenylating its C-terminal glycine residue with ATP, and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding an ubiquitin-E1 thioester and free AMP.The protein encoded by this gene catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation. This gene complements an X-linked mouse temperature-sensitive defect in DNA synthesis, and thus may function in DNA repair. It is part of a gene cluster on chromosome Xp11.23. Alternatively spliced transcript variants that encode the same protein have been described.
Alias Symbols: A1S9, A1S9T, A1ST, GXP1, MGC4781, UBA1A, UBE1, UBE1X, AMCX1, POC20, SMAX2
Protein Interaction Partner: USP5, UBE2D2, UBC, FUS, ISG15, UBTD2, HUWE1, UBE2L3, UBE2D1, SUMO2, CDC34, UBE2K, UBE2W, UBE2R2, UBE2J1, UBE2T, UBE2S, UBE2C, UBE2E3, UBE2H, UBE2G2, UBE2G1, UBE2E2, UBE2E1, UBE2D3, UBE2B, UBE2A, UBI4, MDM2, TRIM25, XPNPEP1, EZR, MC1R, IPO5, FH, CTPS1, ATI
Protein Size: 1058

Poids moléculaire: 116 kDa

ID gène: 7317

NCBI Accession: NM_003334, NP_003325

UniProt: P22314