MYOC anticorps (N-Term)

N° du produit ABIN2774268

Cet anticorps Lapin Polyclonal détecte spécifiquement MYOC dans WB. Il présente une réactivité avec des échantillons de Humain, Rat et Cobaye.

Aperçu rapide pour MYOC anticorps (N-Term) (ABIN2774268)

Antigène: MYOC (Myocilin (MYOC))

Reactivité: Humain, Rat, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MYOC est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-MYOC anticorps

Épitope: N-Term

Fonction: MYOC Antibody - N-terminal region

Séquence: QLTLDQAARP QETQEGLQRE LGTLRRERDQ LETQTRELET AYSNLLRDKS

Homologie: Guinea Pig: 86%, Human: 100%, Rat: 79%

Attributs du produit: This is a rabbit polyclonal antibody against MYOC. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of human MYOC

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP59771-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur MYOC

Antigène: MYOC (Myocilin (MYOC))

Autre désignation: MYOC

Sujet:

Background Information: MYOC encodes the protein myocilin, which is believed to have a role in cytoskeletal function. MYOC is expressed in many occular tissues, including the trabecular meshwork, and was revealed to be the trabecular meshwork glucocorticoid-inducible response protein (TIGR). The trabecular meshwork is a specialized eye tissue essential in regulating intraocular pressure, and mutations in MYOC have been identified as the cause of hereditary juvenile-onset open-angle glaucoma.

Gene Name: myocilin, trabecular meshwork inducible glucocorticoid response

Alternative Symbols: GPOA, JOAG, TIGR, GLC1A, JOAG1

Protein Name: myocilin

Poids moléculaire: 37kDa

ID gène: 4653

NCBI Accession: NP_000252

UniProt: Q99972