Adenylosuccinate Lyase anticorps (Middle Region)

N° du produit ABIN2774275

L’anticorps Lapin Polyclonal anti-Adenylosuccinate Lyase a été validé pour WB et IHC. Il convient pour détecter Adenylosuccinate Lyase dans des échantillons de Humain, Souris, Rat, Chien, Lapin, Cobaye, Cheval, Boeuf (Vache), Porc et Mouton.

Aperçu rapide pour Adenylosuccinate Lyase anticorps (Middle Region) (ABIN2774275)

Antigène: Adenylosuccinate Lyase (ADSL)

Reactivité: Humain, Souris, Rat, Chien, Lapin, Cobaye, Cheval, Boeuf (Vache), Porc, Mouton

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Adenylosuccinate Lyase est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-Adenylosuccinate Lyase anticorps

Épitope: Middle Region

Séquence: RVRDDLRFRG VKGTTGTQAS FLQLFEGDDH KVEQLDKMVT EKAGFKRAFI

Homologie: Cow: 93%, Dog: 86%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 86%, Pig: 93%, Rabbit: 93%, Rat: 86%, Sheep: 93%

Attributs du produit: This is a rabbit polyclonal antibody against ADSL. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human ADSL

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 484 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Adenylosuccinate Lyase

Antigène: Adenylosuccinate Lyase (ADSL)

Autre désignation: ADSL

Sujet: Adenylsuccinate lyase is involved in both de novo synthesis of purines and formation of adenosine monophosphate from inosine monophosphate. It catalyzes two reactions in AMP biosynthesis: the removal of a fumarate from succinylaminoimidazole carboxamide (SAICA) ribotide to give aminoimidazole carboxamide ribotide (AICA) and removal of fumarate from adenylosuccinate to give AMP. Adenylosuccinase deficiency results in succinylpurinemic autism, psychomotor retardation, and , in some cases, growth retardation associated with muscle wasting and epilepsy. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: AMPS, ASASE, ASL
Protein Interaction Partner: CALCOCO2, REL, UBC, PDE12, BTF3L4, NPLOC4, EHD4, UBQLN2, NT5C2, WDR4, PAIP1, PLIN3, SAE1, OXSR1, API5, XPNPEP1, WARS, RAD23B, TWF1, DNAJB1, GTF2I, EIF1AX, DRG2, CTSC, NOV, TYMS, SUMO1, DDA1, USP15, USP4,
Protein Size: 484

Poids moléculaire: 55 kDa

ID gène: 158

NCBI Accession: NM_000026, NP_000017

UniProt: P30566

Pathways: Ribonucleoside Biosynthetic Process