Adenylosuccinate Lyase anticorps (Middle Region)

N° du produit ABIN2774275

L’anticorps anti-Adenylosuccinate Lyase Polyclonal Lapin est utilisé pour la détection de Adenylosuccinate Lyase dans des échantillons de Humain, Souris, Rat, Chien, Cobaye, Cheval, Boeuf (Vache), Porc, Lapin et Mouton. Il a été validé pour WB et IHC.

Aperçu rapide pour Adenylosuccinate Lyase anticorps (Middle Region) (ABIN2774275)

Antigène: Adenylosuccinate Lyase (ADSL)

Reactivité: Humain, Souris, Rat, Chien, Cobaye, Cheval, Boeuf (Vache), Porc, Lapin, Mouton

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Adenylosuccinate Lyase est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-Adenylosuccinate Lyase anticorps

Épitope: Middle Region

Fonction: ADSL Antibody - middle region

Séquence: RVRDDLRFRG VKGTTGTQAS FLQLFEGDDH KVEQLDKMVT EKAGFKRAFI

Homologie: Cow: 93%, Dog: 86%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 86%, Pig: 93%, Rabbit: 93%, Rat: 86%, Sheep: 93%

Attributs du produit: This is a rabbit polyclonal antibody against ADSL. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human ADSL

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP59971-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur Adenylosuccinate Lyase

Antigène: Adenylosuccinate Lyase (ADSL)

Autre désignation: ADSL

Sujet:

Background Information: Adenylsuccinate lyase is involved in both de novo synthesis of purines and formation of adenosine monophosphate from inosine monophosphate. It catalyzes two reactions in AMP biosynthesis: the removal of a fumarate from succinylaminoimidazole carboxamide (SAICA) ribotide to give aminoimidazole carboxamide ribotide (AICA) and removal of fumarate from adenylosuccinate to give AMP. Adenylosuccinase deficiency results in succinylpurinemic autism, psychomotor retardation, and , in some cases, growth retardation associated with muscle wasting and epilepsy. Two transcript variants encoding different isoforms have been found for this gene.

Gene Name: Adenylosuccinate lyase

Alternative Symbols: ASL, AMPS, ASASE

Protein Name: Adenylosuccinate lyase

Poids moléculaire: 55kDa

ID gène: 158

NCBI Accession: NP_000017

UniProt: P30566

Pathways: Ribonucleoside Biosynthetic Process