DAXX anticorps (C-Term)

N° du produit ABIN2774280

Cet anticorps anti-DAXX est un anticorps Lapin Polyclonal détectant DAXX dans WB. Adapté pour Humain, Rat, Cheval et Chien.

Aperçu rapide pour DAXX anticorps (C-Term) (ABIN2774280)

Antigène: DAXX (Death-Domain Associated Protein (DAXX))

Reactivité: Humain, Rat, Cheval, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DAXX est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-DAXX anticorps

Épitope: C-Term

Séquence: VSSTSFNGGV SPHNWGDSGP PCKKSRKEKK QTGSGPLGNS YVERQRSVHE

Homologie: Dog: 85%, Horse: 92%, Human: 100%, Rat: 86%

Attributs du produit: This is a rabbit polyclonal antibody against DAXX. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human DAXX

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur DAXX

Antigène: DAXX (Death-Domain Associated Protein (DAXX))

Autre désignation: DAXX

Sujet: This gene encodes a multifunctional protein that resides in multiple locations in the nucleus and in the cytoplasm. It interacts with a wide variety of proteins, such as apoptosis antigen Fas, centromere protein C, and transcription factor erythroblastosis virus E26 oncogene homolog 1. In the nucleus, the encoded protein functions as a potent transcription repressor that binds to sumoylated transcription factors. Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli. This protein also associates with centromeres in G2 phase. In the cytoplasm, the encoded protein may function to regulate apoptosis. The subcellular localization and function of this protein are modulated by post-translational modifications, including sumoylation, phosphorylation and polyubiquitination.
Protein Interaction Partner: FAM9B, SSX2IP, SUMO1, UBE2I, UBC, GOLGA2, CARD9, PBXIP1, CDCA7L, NECAB2, RASSF1, PML, MDM2, H3F3A, DNMT1, TP53, ATRX, CARM1, PRMT1, WHSC1L1, CUL3, SPOP, HIPK2, PDCD4, DNMT3A, USP7, UBB, RELB, DAXX, CREB1, CBS, ATM, HIST1H4F, HIST1H3C, TRAF3, HIST4H4, BTBD
Protein Size: 710

Poids moléculaire: 78 kDa

ID gène: 1616

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway