Cathepsin L anticorps (C-Term)

N° du produit ABIN2774366

L’anticorps Lapin Polyclonal anti-Cathepsin L a été validé pour WB. Il convient pour détecter Cathepsin L dans des échantillons de Humain, Souris, Rat et Mouton.

Aperçu rapide pour Cathepsin L anticorps (C-Term) (ABIN2774366)

Antigène: Cathepsin L (CTSL1) (Cathepsin L1 (CTSL1))

Reactivité: Humain, Souris, Rat, Mouton

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cathepsin L est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Cathepsin L anticorps

Épitope: C-Term

Séquence: GGLDSEESYP YEATEESCKY NPKYSVANDT GFVDIPKQEK ALMKAVATVG

Homologie: Human: 100%, Mouse: 77%, Rat: 77%, Sheep: 77%

Attributs du produit: This is a rabbit polyclonal antibody against CTSL1. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 333 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Cathepsin L

Antigène: Cathepsin L (CTSL1) (Cathepsin L1 (CTSL1))

Autre désignation: CTSL1

Sujet: The protein encoded by this gene is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. The encoded protein has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. This protein, which is a member of the peptidase C1 family, is a dimer composed of disulfide-linked heavy and light chains, both produced from a single protein precursor. At least two transcript variants encoding the same protein have been found for this gene.
Alias Symbols: CATL, CTSL, FLJ31037, MEP, CTSL1
Protein Interaction Partner: SGTA, SERPINB3, BTN3A3, RELB, PPP1CC, APOA1, ALB, UBC, EED, BAG6, GEM, ARSA, SERPINB13, CST3, CST7, CTSC, CSTB, KNG1, PLAU, TG, CD7, CSTA, RXRA, CXCL8, IGFBP3, CD74, GCG, COL18A1, CUX1, CTSL, SLPI,
Protein Size: 333

Poids moléculaire: 36 kDa

ID gène: 1514

NCBI Accession: NM_145918, NP_666023

UniProt: P07711

Pathways: Activation of Innate immune Response, Toll-Like Receptors Cascades