Cathepsin L anticorps (C-Term)

N° du produit ABIN2774366

Détail du produit anti-Cathepsin L anticorps

Antigène: Cathepsin L (CTSL1) (Cathepsin L1 (CTSL1))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Mouton

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cathepsin L est non-conjugé

Application: Western Blotting (WB)

Séquence: GGLDSEESYP YEATEESCKY NPKYSVANDT GFVDIPKQEK ALMKAVATVG

Homologie: Human: 100%, Mouse: 77%, Rat: 77%, Sheep: 77%

Attributs du produit: This is a rabbit polyclonal antibody against CTSL1. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 333 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Cathepsin L

Antigène: Cathepsin L (CTSL1) (Cathepsin L1 (CTSL1))

Autre désignation: CTSL1 (CTSL1 Produits)

Synonymes: anticorps CATL, anticorps CTSL1, anticorps MEP, anticorps 1190035F06Rik, anticorps Ctsl1, anticorps fs, anticorps nkt, anticorps CATHL, anticorps CatL, anticorps Ctsl, anticorps CTSL, anticorps mep, anticorps catl, anticorps ctsl, anticorps cpl-1, anticorps MGC80629, anticorps MGC107932, anticorps LOC663234, anticorps 26-29-p, anticorps Cp1, anticorps si:dkey-121a11.6, anticorps CTSV, anticorps catL, anticorps cb15, anticorps ctsl1b, anticorps hgg1, anticorps wu:fb30g09, anticorps zgc:92089, anticorps cathepsin L, anticorps cathepsin V, anticorps cathepsin L L homeolog, anticorps cathepsin L1, anticorps Cathepsin L1, anticorps Cathepsin L, anticorps testin gene, anticorps cathepsin 12, anticorps cathepsin Lb, anticorps cathepsin L.1, anticorps CTSL, anticorps Ctsl, anticorps CTSV, anticorps ctsl.L, anticorps ctsl, anticorps LOC100008830, anticorps catl1, anticorps 26-29-p, anticorps catl, anticorps Tsp_11596, anticorps Testin, anticorps cts12, anticorps LOC102156614, anticorps ctslb, anticorps ctsl.1

Sujet: The protein encoded by this gene is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. The encoded protein has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. This protein, which is a member of the peptidase C1 family, is a dimer composed of disulfide-linked heavy and light chains, both produced from a single protein precursor. At least two transcript variants encoding the same protein have been found for this gene.
Alias Symbols: CATL, CTSL, FLJ31037, MEP, CTSL1
Protein Interaction Partner: SGTA, SERPINB3, BTN3A3, RELB, PPP1CC, APOA1, ALB, UBC, EED, BAG6, GEM, ARSA, SERPINB13, CST3, CST7, CTSC, CSTB, KNG1, PLAU, TG, CD7, CSTA, RXRA, CXCL8, IGFBP3, CD74, GCG, COL18A1, CUX1, CTSL, SLPI,
Protein Size: 333

Poids moléculaire: 36 kDa

ID gène: 1514

NCBI Accession: NM_145918, NP_666023

UniProt: P07711

Pathways: Activation of Innate immune Response, Toll-Like Receptors Cascades