PDIA3 anticorps (C-Term)
Aperçu rapide pour PDIA3 anticorps (C-Term) (ABIN2774375)
Antigène
Voir toutes PDIA3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Séquence
- YFSPANKKLN PKKYEGGREL SDFISYLQRE ATNPPVIQEE KPKKKKKAQE
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Homologie
- Cow: 93%, Dog: 100%, Goat: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 92%, Rabbit: 93%, Rat: 100%, Sheep: 93%, Zebrafish: 86%
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Attributs du produit
- This is a rabbit polyclonal antibody against PDIA3. It was validated on Western Blot.
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Purification
- Affinity Purified
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 505 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- PDIA3 (Protein Disulfide Isomerase Family A, Member 3 (PDIA3))
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Autre désignation
- PDIA3
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Sujet
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This gene encodes a protein of the endoplasmic reticulum that interacts with lectin chaperones calreticulin and calnexin to modulate folding of newly synthesized glycoproteins. The protein was once thought to be a phospholipase, however, it has been demonstrated that the protein actually has protein disulfide isomerase activity. It is thought that complexes of lectins and this protein mediate protein folding by promoting formation of disulfide bonds in their glycoprotein substrates.
Alias Symbols: ER60, ERp57, ERp60, ERp61, GRP57, GRP58, HsT17083, P58, PI-PLC
Protein Interaction Partner: FUS, UBC, MDM2, SUZ12, ABCE1, RBBP4, RAB1A, PGD, MTAP, MTPN, BCCIP, CNDP2, NANS, DAK, ACOT7, NPEPPS, SLC9A3R1, RPL23, SMS, LDHA, HSPD1, CSE1L, ATP6V1A, ADSS, EGFR, UBD, CANX, CALR, HDAC10, MTOR, EFEMP1, ATF2, COL6A1, CLU, APP, ADAM10, AGRN, DCBLD1, RICTOR
Protein Size: 505 -
Poids moléculaire
- 56 kDa
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ID gène
- 2923
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NCBI Accession
- NM_005313, NP_005304
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UniProt
- P30101
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Pathways
- Maintenance of Protein Location, Protein targeting to Nucleus, Cell RedoxHomeostasis
Antigène
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