PICALM anticorps (C-Term)

N° du produit ABIN2774386

Cet anticorps Lapin Polyclonal détecte spécifiquement PICALM dans WB et IHC. Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin et Poisson zèbre (Danio rerio).

Aperçu rapide pour PICALM anticorps (C-Term) (ABIN2774386)

Antigène: PICALM (Phosphatidylinositol Binding clathrin Assembly Protein (PICALM))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PICALM est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-PICALM anticorps

Épitope: C-Term

Fonction: PICALM Antibody - C-terminal region

Séquence: DLDSSLANLV GNLGIGNGTT KNDVNWSQPG EKKLTGGSNW QPKVAPTTAW

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Attributs du produit: This is a rabbit polyclonal antibody against PICALM. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP63958-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur PICALM

Antigène: PICALM (Phosphatidylinositol Binding clathrin Assembly Protein (PICALM))

Autre désignation: PICALM

Sujet:

Background Information: This gene encodes a clathrin assembly protein, which recruits clathrin and adaptor protein complex 2 (AP2) to cell membranes at sites of coated-pit formation and clathrin-vesicle assembly. The protein may be required to determine the amount of membrane to be recycled, possibly by regulating the size of the clathrin cage. The protein is involved in AP2-dependent clathrin-mediated endocytosis at the neuromuscular junction. A chromosomal translocation t(10,11)(p13,q14) leading to the fusion of this gene and the MLLT10 gene is found in acute lymphoblastic leukemia, acute myeloid leukemia and malignant lymphomas. The polymorphisms of this gene are associated with the risk of Alzheimer disease.

Gene Name: Phosphatidylinositol binding clathrin assembly protein

Alternative Symbols: LAP, CALM, CLTH

Protein Name: Phosphatidylinositol-binding clathrin assembly protein Ensembl ENSP00000434884

Poids moléculaire: 60kDa

ID gène: 8301

NCBI Accession: NP_001193876

UniProt: E9PN05

Pathways: Synaptic Membrane