THOC7 anticorps (C-Term)

N° du produit ABIN2774475

L’anticorps anti-THOC7 Polyclonal Lapin est utilisé pour la détection de THOC7 dans des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin et Poisson zèbre (Danio rerio). Il a été validé pour WB.

Aperçu rapide pour THOC7 anticorps (C-Term) (ABIN2774475)

Antigène: THOC7 (THO Complex 7 (THOC7))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp THOC7 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-THOC7 anticorps

Épitope: C-Term

Fonction: THOC7 Antibody - C-terminal region

Séquence: ELEHLSHIKE SVEDKLELRR KQFHVLLSTI HELQQTLEND EKLSEVEEAQ

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 100%, Rat: 100%, Zebrafish: 90%

Attributs du produit: This is a rabbit polyclonal antibody against THOC7. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human THOC7

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP67323-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur THOC7

Antigène: THOC7 (THO Complex 7 (THOC7))

Autre désignation: THOC7

Sujet:

Targeted Subunit: 7 homolog

Background Information: THOC7 is a component of the THO subcomplex of the TREX complex. The TREX complex specifically associates with spliced mRNA and not with unspliced pre-mRNA. It is recruited to spliced mRNAs by a transcription-independent mechanism. Binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export. The recruitment occurs via an interaction between ALYREF/THOC4 and the cap-binding protein NCBP1. DDX39B functions as a bridge between ALYREF/THOC4 and the THO complex. The TREX complex is essential for the export of Kaposi's sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production. The recruitment of the TREX complex to the intronless viral mRNA occurs via an interaction between KSHV ORF57 protein and ALYREF/THOC4.

Alternative Symbols: fSAP24, hTREX30, NIF3L1BP1

Protein Name: THO complex subunit 7 homolog

Poids moléculaire: 22kDa

ID gène: 80145

NCBI Accession: NP_079351

UniProt: Q6I9Y2