HIST1H4A anticorps (N-Term)

N° du produit ABIN2774551

Détail du produit anti-HIST1H4A anticorps

Antigène: HIST1H4A (Histone Cluster 1, H4a (HIST1H4A))

Épitope: N-Term

Reactivité: Souris, Rat, Boeuf (Vache), Poisson zèbre (Danio rerio), Chévre, Cobaye, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HIST1H4A est non-conjugé

Application: Western Blotting (WB)

Séquence: LGKGGAKRHR KVLRDNIQGI TKPAIRRLAR RGGVKRISGL IYEETRGVLK

Homologie: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against HIST1H4A. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of Human HIST1H4A

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur HIST1H4A

Antigène: HIST1H4A (Histone Cluster 1, H4a (HIST1H4A))

Autre désignation: HIST1H4A (HIST1H4A Produits)

Synonymes: anticorps Hist1h4a, anticorps H4FA, anticorps histone cluster 1, H3f, anticorps histone cluster 1 H4 family member a, anticorps histone cluster 1, H4a, anticorps Hist1h3f, anticorps HIST1H4A, anticorps Hist1h4a

Sujet: HIST1H4A is a core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Alias Symbols: H4/p
Protein Interaction Partner: UBC, DTX3L, RBBP4, H3F3A, CENPA, HIST1H3A, HDAC2, ASB9, ASB16, L3MBTL2, rev, ARFIP1, JMJD6, XPO7, FAF1, HSPH1, SEC23A, PRMT3, RBX1, HIRIP3, CUL1, ZYX, SF1, TTC1, TROVE2, SHMT1, RPL24, PPM1G, OSBP, GFPT1, GARS, CARS, FBXO6, PAN2, PRMT8, RL1, HCVgp1, ITGA4,
Protein Size: 103

Poids moléculaire: 11 kDa

ID gène: 8359

NCBI Accession: NM_175054, NP_778224

UniProt: P62805