ADAR anticorps (N-Term)

N° du produit ABIN2774648

Il existe 1 publication pour ce produit. L’anticorps anti-ADAR Polyclonal Lapin est utilisé pour la détection de ADAR dans des échantillons de Humain. Il a été validé pour WB et IHC.

Aperçu rapide pour ADAR anticorps (N-Term) (ABIN2774648)

Antigène: ADAR (Adenosine Deaminase, RNA-Specific (ADAR))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ADAR est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-ADAR anticorps

Épitope: N-Term

Fonction: ADAR Antibody - N-terminal region

Séquence: GEGKATTAHD LSGKLGTPKK EINRVLYSLA KKGKLQKEAG TPPLWKIAVS

Homologie: Human: 100%

Attributs du produit: This is a rabbit polyclonal antibody against ADAR. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human ADAR

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP36715-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-ADAR (ABIN2774648)

Pan, Ye, Franco, Li, Yu, Zou, Zhang, Jiao, Lin: "Insulin resistance and depressive symptoms in middle-aged and elderly Chinese: findings from the Nutrition and Health of Aging Population in China Study." dans: Journal of affective disorders, Vol. 109, Issue 1-2, pp. 75-82, (2008) (PubMed).

Détails sur ADAR

Antigène: ADAR (Adenosine Deaminase, RNA-Specific (ADAR))

Autre désignation: ADAR

Sujet:

Background Information: ADAR is responsible for RNA editing by site-specific deamination of adenosines. This enzyme destabilizes double stranded RNA through conversion of adenosine to inosine. Mutations in this gene have been associated with dyschromatosis symmetrica hereditaria. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.This gene encodes the enzyme responsible for RNA editing by site-specific deamination of adenosines. This enzyme destabilizes double stranded RNA through conversion of adenosine to inosine. Mutations in this gene have been associated with dyschromatosis symmetrica hereditaria. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Gene Name: Adenosine deaminase, RNA-specific

Alternative Symbols: DSH, AGS6, G1P1, IFI4, P136, ADAR1, DRADA, DSRAD, IFI-4, K88DSRBP

Protein Name: Double-stranded RNA-specific adenosine deaminase

Poids moléculaire: 136kDa

ID gène: 103

NCBI Accession: NP_001102

UniProt: P55265

Pathways: Protein targeting to Nucleus