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FBXO2 anticorps (C-Term)

FBXO2 Reactivité: Humain, Souris, Rat, Chien, Cheval, Boeuf (Vache), Cobaye, Poisson zèbre (Danio rerio), Lapin WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2774692
  • Antigène Voir toutes FBXO2 Anticorps
    FBXO2 (F-Box Protein 2 (FBXO2))
    Épitope
    • 15
    • 10
    • 8
    • 7
    • 5
    • 2
    • 1
    • 1
    C-Term
    Reactivité
    Humain, Souris, Rat, Chien, Cheval, Boeuf (Vache), Cobaye, Poisson zèbre (Danio rerio), Lapin
    Hôte
    • 38
    • 4
    Lapin
    Clonalité
    • 40
    • 2
    Polyclonal
    Conjugué
    • 18
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp FBXO2 est non-conjugé
    Application
    • 41
    • 19
    • 14
    • 13
    • 13
    • 5
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    LAEFATGQVA VPEDGSWMEI SHTFIDYGPG VRFVRFEHGG QDSVYWKGWF
    Homologie
    Cow: 92%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 85%, Rat: 93%, Zebrafish: 77%
    Attributs du produit
    This is a rabbit polyclonal antibody against Fbxo2. It was validated on Western Blot.
    Purification
    Affinity Purified
    Top Product
    Discover our top product FBXO2 Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 297 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    FBXO2 (F-Box Protein 2 (FBXO2))
    Autre désignation
    Fbxo2 (FBXO2 Produits)
    Synonymes
    anticorps FBG1, anticorps FBX2, anticorps Fbs1, anticorps NFB42, anticorps OCP1, anticorps Fbs2, anticorps Prpl4, anticorps F-box protein 2, anticorps FBXO2, anticorps Fbxo2
    Sujet
    Fbxo2 is a substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Involved in the endoplasmic reticulum-associated degradation pathway (ERAD) for misfolded lumenal proteins by recognizing and binding sugar chains on unfolded glycoproteins that are retrotranslocated into the cytosol and promoting their ubiquitination and subsequent degradation. Prevents formation of cytosolic aggregates of unfolded glycoproteins that have been retrotranslocated into the cytosol. Able to recognize and bind denatured glycoproteins, preferentially those of the high-mannose type.
    Alias Symbols: FBG1, FBX2, Fbs1, Fbs2, MGC54895, NFB42, Prpl4
    Protein Interaction Partner: Stat1, Cul1, Skp1a, Bace1, Vcp,
    Protein Size: 297
    Poids moléculaire
    34 kDa
    ID gène
    230904
    NCBI Accession
    NM_176848, NP_789818
    UniProt
    Q80UW2
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