FBXW11 anticorps (N-Term)

N° du produit ABIN2774702

Cité dans 1 publication. Cet anticorps anti-FBXW11 Polyclonal Lapin (ABIN2774702) détecte spécifiquement FBXW11 dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Lapin, Cheval et Poisson zèbre (Danio rerio).

Aperçu rapide pour FBXW11 anticorps (N-Term) (ABIN2774702)

Antigène: FBXW11 (F-Box and WD Repeat Domain Containing 11 (FBXW11))

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Lapin, Cheval, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FBXW11 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-FBXW11 anticorps

Épitope: N-Term

Fonction: FBXW11 Antibody - N-terminal region

Séquence: CLQSMPSVRC LQISNGTSSV IVSRKRPSEG NYQKEKDLCI KYFDQWSESD

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Attributs du produit: This is a rabbit polyclonal antibody against FBXW11. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human FBXW11

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP43129-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-FBXW11 (ABIN2774702)

Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." dans: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

Détails sur FBXW11

Antigène: FBXW11 (F-Box and WD Repeat Domain Containing 11 (FBXW11))

Autre désignation: FBXW11

Sujet:

Background Information: FBXW11 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class and, in addition to an F-box, contains multiple WD40 repeats.This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class and, in addition to an F-box, contains multiple WD40 repeats. This gene contains at least 14 exons, and its alternative splicing generates 3 transcript variants diverging at the presence/absence of two alternate exons.

Gene Name: F-box and WD repeat domain containing 11

Alternative Symbols: Hos, BTRC2, FBW1B, Fbw11, BTRCP2, FBXW1B, NEDJED

Protein Name: F-box/WD repeat-containing protein 11

Poids moléculaire: 62kDa

ID gène: 23291

NCBI Accession: NP_036432

UniProt: Q9UKB1