RNF19A anticorps (N-Term)

N° du produit ABIN2774733

Cet anticorps anti-RNF19A est un anticorps Lapin Polyclonal détectant RNF19A dans WB. Adapté pour Humain, Souris, Boeuf (Vache), Chien, Cheval, Porc, Cobaye, Lapin et Rat.

Aperçu rapide pour RNF19A anticorps (N-Term) (ABIN2774733)

Antigène: RNF19A (Ring Finger Protein 19A (RNF19A))

Reactivité: Humain, Souris, Boeuf (Vache), Chien, Cheval, Porc, Cobaye, Lapin, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RNF19A est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-RNF19A anticorps

Épitope: N-Term

Séquence: IFSTNTSSDN GLTSISKQIG DFIECPLCLL RHSKDRFPDI MTCHHRSCVD

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against RNF19A. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human RNF19A

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 838 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur RNF19A

Antigène: RNF19A (Ring Finger Protein 19A (RNF19A))

Autre désignation: RNF19A

Sujet: RNF19A contains two RING-finger motifs and an IBR (in between RING fingers) motif. This protein is an E3 ubiquintin ligase that is localized in Lewy bodies (LBs), a characteristic neuronal inclusion in Parkinson's disease (PD) brains. This protein interacts with UBE2L3/UBCH7 and UBE2E2/UBCH8, but not other ubiquitin-conjugating enzymes. This protein is found to bind and ubiquitylate synphilin 1 (SNCAIP), which is a interacting protein of alpha synuclein in neurons, and a major component of LB.The protein encoded this gene contains two RING-finger motifs and an IBR (in between RING fingers) motif. This protein is an E3 ubiquintin ligase that is localized in Lewy bodies (LBs), a characteristic neuronal inclusion in Parkinson's disease (PD) brains. This protein interacts with UBE2L3/UBCH7 and UBE2E2/UBCH8, but not other ubiquitin-conjugating enzymes. This protein is found to bind and ubiquitylate synphilin 1 (SNCAIP), which is a interacting protein of alpha synuclein in neurons, and a major component of LB. Alternatively spliced transcript variants encoding the same protein have been reported.
Alias Symbols: DKFZp566B1346, DORFIN, RNF19
Protein Interaction Partner: UBC, UBE2L3, Psmc3, ZAK, NUDT21, C11orf58, RPS6KA5, MAP3K7, ILK, SOD1, VCP, SNCAIP, CASR, UBE2E2, SUFU, TUBG2, UBE2L6, TUBG1,
Protein Size: 838

Poids moléculaire: 91 kDa

ID gène: 25897

NCBI Accession: NM_015435, NP_056250

UniProt: Q9NV58