RNF19A anticorps (N-Term)

N° du produit ABIN2774733

Cet anticorps anti-RNF19A Polyclonal Lapin (ABIN2774733) détecte spécifiquement RNF19A dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris, Boeuf (Vache), Chien, Cheval, Porc, Cobaye, Lapin et Rat.

Aperçu rapide pour RNF19A anticorps (N-Term) (ABIN2774733)

Antigène: RNF19A (Ring Finger Protein 19A (RNF19A))

Reactivité: Humain, Souris, Boeuf (Vache), Chien, Cheval, Porc, Cobaye, Lapin, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RNF19A est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-RNF19A anticorps

Épitope: N-Term

Fonction: RNF19A Antibody - N-terminal region

Séquence: IFSTNTSSDN GLTSISKQIG DFIECPLCLL RHSKDRFPDI MTCHHRSCVD

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against RNF19A. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human RNF19A

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP43197-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur RNF19A

Antigène: RNF19A (Ring Finger Protein 19A (RNF19A))

Autre désignation: RNF19A

Sujet:

Background Information: RNF19A contains two RING-finger motifs and an IBR (in between RING fingers) motif. This protein is an E3 ubiquintin ligase that is localized in Lewy bodies (LBs), a characteristic neuronal inclusion in Parkinson's disease (PD) brains. This protein interacts with UBE2L3/UBCH7 and UBE2E2/UBCH8, but not other ubiquitin-conjugating enzymes. This protein is found to bind and ubiquitylate synphilin 1 (SNCAIP), which is a interacting protein of alpha synuclein in neurons, and a major component of LB.The protein encoded this gene contains two RING-finger motifs and an IBR (in between RING fingers) motif. This protein is an E3 ubiquintin ligase that is localized in Lewy bodies (LBs), a characteristic neuronal inclusion in Parkinson's disease (PD) brains. This protein interacts with UBE2L3/UBCH7 and UBE2E2/UBCH8, but not other ubiquitin-conjugating enzymes. This protein is found to bind and ubiquitylate synphilin 1 (SNCAIP), which is a interacting protein of alpha synuclein in neurons, and a major component of LB. Alternatively spliced transcript variants encoding the same protein have been reported.

Gene Name: Ring finger protein 19A, E3 ubiquitin protein ligase

Alternative Symbols: RNF19

Protein Name: E3 ubiquitin-protein ligase RNF19A

Poids moléculaire: 91kDa

ID gène: 25897

NCBI Accession: NP_056250

UniProt: Q9NV58