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RNF19A anticorps (N-Term)

RNF19A Reactivité: Humain, Souris, Chien, Porc, Boeuf (Vache), Cheval, Cobaye, Lapin, Rat WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2774733
  • Antigène Voir toutes RNF19A Anticorps
    RNF19A (Ring Finger Protein 19A (RNF19A))
    Épitope
    • 15
    • 8
    • 7
    • 6
    • 6
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    Humain, Souris, Chien, Porc, Boeuf (Vache), Cheval, Cobaye, Lapin, Rat
    Hôte
    • 48
    • 1
    • 1
    Lapin
    Clonalité
    • 49
    • 1
    Polyclonal
    Conjugué
    • 15
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp RNF19A est non-conjugé
    Application
    • 36
    • 26
    • 15
    • 13
    • 13
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    IFSTNTSSDN GLTSISKQIG DFIECPLCLL RHSKDRFPDI MTCHHRSCVD
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%
    Attributs du produit
    This is a rabbit polyclonal antibody against RNF19A. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the N terminal region of human RNF19A
    Top Product
    Discover our top product RNF19A Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 838 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    RNF19A (Ring Finger Protein 19A (RNF19A))
    Autre désignation
    RNF19A (RNF19A Produits)
    Synonymes
    anticorps RNF19, anticorps RNF19A, anticorps AA032313, anticorps Dorfin, anticorps Rnf19, anticorps UIP117, anticorps Ubce7ip2, anticorps XYbp, anticorps ring finger protein 19A, RBR E3 ubiquitin protein ligase, anticorps ring finger protein 19A, anticorps RNF19A, anticorps Rnf19a
    Sujet
    RNF19A contains two RING-finger motifs and an IBR (in between RING fingers) motif. This protein is an E3 ubiquintin ligase that is localized in Lewy bodies (LBs), a characteristic neuronal inclusion in Parkinson's disease (PD) brains. This protein interacts with UBE2L3/UBCH7 and UBE2E2/UBCH8, but not other ubiquitin-conjugating enzymes. This protein is found to bind and ubiquitylate synphilin 1 (SNCAIP), which is a interacting protein of alpha synuclein in neurons, and a major component of LB.The protein encoded this gene contains two RING-finger motifs and an IBR (in between RING fingers) motif. This protein is an E3 ubiquintin ligase that is localized in Lewy bodies (LBs), a characteristic neuronal inclusion in Parkinson's disease (PD) brains. This protein interacts with UBE2L3/UBCH7 and UBE2E2/UBCH8, but not other ubiquitin-conjugating enzymes. This protein is found to bind and ubiquitylate synphilin 1 (SNCAIP), which is a interacting protein of alpha synuclein in neurons, and a major component of LB. Alternatively spliced transcript variants encoding the same protein have been reported.
    Alias Symbols: DKFZp566B1346, DORFIN, RNF19
    Protein Interaction Partner: UBC, UBE2L3, Psmc3, ZAK, NUDT21, C11orf58, RPS6KA5, MAP3K7, ILK, SOD1, VCP, SNCAIP, CASR, UBE2E2, SUFU, TUBG2, UBE2L6, TUBG1,
    Protein Size: 838
    Poids moléculaire
    91 kDa
    ID gène
    25897
    NCBI Accession
    NM_015435, NP_056250
    UniProt
    Q9NV58
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