MARCH2 anticorps (C-Term)
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- Antigène Voir toutes MARCH2 Anticorps
- MARCH2 (Membrane-Associated Ring Finger (C3HC4) 2, E3 Ubiquitin Protein Ligase (MARCH2))
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Épitope
- C-Term
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Reactivité
- Humain, Rat, Souris, Cobaye, Lapin, Chien
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp MARCH2 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- TIALFTIYVL WTLVSFRYHC QLYSEWRKTN QKVRLKIREA DSPEGPQHSP
- Homologie
- Dog: 92%, Guinea Pig: 86%, Human: 100%, Mouse: 100%, Rabbit: 77%, Rat: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against MARCH2. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the C terminal region of human MARCH2
- Top Product
- Discover our top product MARCH2 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 246 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Long-term results of saphenous vein graft for coronary stenosis caused by Kawasaki disease." dans: Circulation journal : official journal of the Japanese Circulation Society, Vol. 73, Issue 1, pp. 73-7, (2008) (PubMed).
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Long-term results of saphenous vein graft for coronary stenosis caused by Kawasaki disease." dans: Circulation journal : official journal of the Japanese Circulation Society, Vol. 73, Issue 1, pp. 73-7, (2008) (PubMed).
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- Antigène
- MARCH2 (Membrane-Associated Ring Finger (C3HC4) 2, E3 Ubiquitin Protein Ligase (MARCH2))
- Autre désignation
- MARCH2 (MARCH2 Produits)
- Synonymes
- anticorps MARCH-II, anticorps RNF172, anticorps rgd1306395, anticorps marh2, anticorps RGD1306395, anticorps 9530046H09Rik, anticorps membrane associated ring-CH-type finger 2, anticorps membrane associated ring-CH-type finger 2 S homeolog, anticorps E3 ubiquitin-protein ligase MARCH2, anticorps membrane-associated ring finger (C3HC4) 2, anticorps MARCH2, anticorps march2.S, anticorps march2, anticorps Tsp_09446, anticorps marh2, anticorps March2
- Sujet
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MARCH2 is an E3 ubiquitin-protein ligase that may mediate ubiquitination of TFRC and CD86, and promote their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. MARCH2 may be involved in endosomal trafficking through interaction with STX6.
Alias Symbols: HSPC240, MARCH-II, RNF172
Protein Interaction Partner: LDLRAD1, SYNE4, CCDC155, FATE1, UBE2H, UBE2D1, CDC34, GOPC, STX6, CFTR, ADRB2, ELAVL1, DLG1,
Protein Size: 246 - Poids moléculaire
- 27 kDa
- ID gène
- 51257
- NCBI Accession
- NM_016496, NP_057580
- UniProt
- Q9P0N8
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