MARCH2 anticorps (C-Term)

N° du produit ABIN2774742

Cet anticorps Lapin Polyclonal détecte spécifiquement MARCH2 dans WB. Il présente une réactivité avec des échantillons de Humain, Rat, Souris, Cobaye, Lapin et Chien.Il a été cité dans 1 publication.

Aperçu rapide pour MARCH2 anticorps (C-Term) (ABIN2774742)

Antigène: MARCH2 (Membrane-Associated Ring Finger (C3HC4) 2, E3 Ubiquitin Protein Ligase (MARCH2))

Reactivité: Humain, Rat, Souris, Cobaye, Lapin, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MARCH2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-MARCH2 anticorps

Épitope: C-Term

Séquence: TIALFTIYVL WTLVSFRYHC QLYSEWRKTN QKVRLKIREA DSPEGPQHSP

Homologie: Dog: 92%, Guinea Pig: 86%, Human: 100%, Mouse: 100%, Rabbit: 77%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against MARCH2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human MARCH2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 246 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-MARCH2 (ABIN2774742)

Wakisaka, Tsuda, Yamada, Yagihara, Kitamura: "Long-term results of saphenous vein graft for coronary stenosis caused by Kawasaki disease." dans: Circulation journal : official journal of the Japanese Circulation Society, Vol. 73, Issue 1, pp. 73-7, (2008) (PubMed).

Détails sur MARCH2

Antigène: MARCH2 (Membrane-Associated Ring Finger (C3HC4) 2, E3 Ubiquitin Protein Ligase (MARCH2))

Autre désignation: MARCH2

Sujet: MARCH2 is an E3 ubiquitin-protein ligase that may mediate ubiquitination of TFRC and CD86, and promote their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. MARCH2 may be involved in endosomal trafficking through interaction with STX6.
Alias Symbols: HSPC240, MARCH-II, RNF172
Protein Interaction Partner: LDLRAD1, SYNE4, CCDC155, FATE1, UBE2H, UBE2D1, CDC34, GOPC, STX6, CFTR, ADRB2, ELAVL1, DLG1,
Protein Size: 246

Poids moléculaire: 27 kDa

ID gène: 51257

NCBI Accession: NM_016496, NP_057580

UniProt: Q9P0N8