MARCH5 anticorps (N-Term)

N° du produit ABIN2774746

Il existe 1 publication pour ce produit. L’anticorps anti-MARCH5 Polyclonal Lapin est utilisé pour la détection de MARCH5 dans des échantillons de Humain, Souris, Rat, Boeuf (Vache), Poisson zèbre (Danio rerio), Chien, Cobaye, Cheval et Lapin. Il a été validé pour WB.

Aperçu rapide pour MARCH5 anticorps (N-Term) (ABIN2774746)

Antigène: MARCH5 (Membrane-Associated Ring Finger (C3HC4) 5 (MARCH5))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Poisson zèbre (Danio rerio), Chien, Cobaye, Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MARCH5 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-MARCH5 anticorps

Épitope: N-Term

Fonction: MARCH5 Antibody - N-terminal region

Séquence: CRGSTKWVHQ ACLQRWVDEK QRGNSTARVA CPQCNAEYLI VFPKLGPVVY

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against MARCH5. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human MARCH5

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP43232-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-MARCH5 (ABIN2774746)

Cilenti, Ambivero, Ward, Alnemri, Germain, Zervos: "Inactivation of Omi/HtrA2 protease leads to the deregulation of mitochondrial Mulan E3 ubiquitin ligase and increased mitophagy." dans: Biochimica et biophysica acta, Vol. 1843, Issue 7, pp. 1295-307, (2014) (PubMed).

Détails sur MARCH5

Antigène: MARCH5 (Membrane-Associated Ring Finger (C3HC4) 5 (MARCH5))

Autre désignation: MARCH5

Sujet:

Background Information: MARCH5 is an ubiquitin ligase of the mitochondrial outer membrane that plays a role in the control of mitochondrial morphology by regulating mitofusin-2 (MFN2) and DRP1 (DNM1L). MARCH5 is a ubiquitin ligase of the mitochondrial outer membrane that plays a role in the control of mitochondrial morphology by regulating mitofusin-2 (MFN2, MIM 608507) and DRP1 (DNM1L, MIM 603850) (Nakamura et al., 2006 [PubMed 16936636]).[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-1502 AK000452.1 3-1504 1503-1863 BC015480.1 1463-1823 1864-1901 BE393612.1 438-475 1902-3713 BC015480.1 1852-3663 3714-3941 BC015480.1 3669-3896

Gene Name: Membrane-associated ring finger (C3HC4) 5

Alternative Symbols: MITOL, MARCH5, RNF153, MARCH-V

Protein Name: E3 ubiquitin-protein ligase MARCH5

Poids moléculaire: 31kDa

ID gène: 54708

NCBI Accession: NP_060294

UniProt: Q9NX47