Annexin A3 anticorps (N-Term)
Aperçu rapide pour Annexin A3 anticorps (N-Term) (ABIN2774839)
Antigène
Voir toutes Annexin A3 (ANXA3) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Séquence
- MASIWVGHRG TVRDYPDFSP SVDAEAIQKA IRGIGTDEKM LISILTERSN
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Homologie
- Dog: 79%, Guinea Pig: 79%, Horse: 86%, Human: 100%, Mouse: 79%, Rabbit: 93%, Rat: 79%
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Attributs du produit
- This is a rabbit polyclonal antibody against ANXA3. It was validated on Western Blot and immunohistochemistry.
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Purification
- Protein A purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human ANXA3
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 323 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Nephrotic syndrome and subepithelial deposits in a mouse model of immune-mediated anti-podocyte glomerulonephritis." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 187, Issue 6, pp. 3218-29, (2011) (PubMed).
: "Primary cell cultures from human renal cortex and renal-cell carcinoma evidence a differential expression of two spliced isoforms of Annexin A3." dans: The American journal of pathology, Vol. 176, Issue 4, pp. 1660-70, (2010) (PubMed).
: "Alterations of the podocyte proteome in response to high glucose concentrations." dans: Proteomics, Vol. 9, Issue 19, pp. 4519-28, (2009) (PubMed).
: "Combined analysis of transcriptome and proteome data as a tool for the identification of candidate biomarkers in renal cell carcinoma." dans: Proteomics, Vol. 9, Issue 6, pp. 1567-81, (2009) (PubMed).
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: "Nephrotic syndrome and subepithelial deposits in a mouse model of immune-mediated anti-podocyte glomerulonephritis." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 187, Issue 6, pp. 3218-29, (2011) (PubMed).
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- Annexin A3 (ANXA3)
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Autre désignation
- ANXA3
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Sujet
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The ANXA3 gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions in the inhibition of phopholipase A2 and cleavage of inositol 1,2-cyclic phosphate to form inositol 1-phosphate. This protein may also play a role in anti-coagulation.
Alias Symbols: ANX3
Protein Interaction Partner: UBC, ATF2, SNAP23, STXBP2, STX4, ANXA11, ANXA4, ISG15, EMG1, IGSF21, UBR1, UNC119, TP53, REG3A,
Protein Size: 323 -
Poids moléculaire
- 36 kDa
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ID gène
- 306
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NCBI Accession
- NM_005139, NP_005130
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UniProt
- P12429
Antigène
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