GJB2 anticorps (N-Term)

N° du produit ABIN2774858

L’anticorps anti-GJB2 Polyclonal Lapin est utilisé pour la détection de GJB2 dans des échantillons de Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Cheval, Lapin et Mouton. Il a été validé pour WB.

Aperçu rapide pour GJB2 anticorps (N-Term) (ABIN2774858)

Antigène: GJB2 (Gap Junction Protein, beta 2, 26kDa (GJB2))

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Cheval, Lapin, Mouton

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GJB2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-GJB2 anticorps

Épitope: N-Term

Fonction: GJB2 Antibody - middle region

Séquence: STPALLVAMH VAYRRHEKKR KFIKGEIKSE FKDIEEIKTQ KVRIEGSLWW

Homologie: Cow: 86%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 79%, Rat: 93%, Sheep: 86%

Attributs du produit: This is a rabbit polyclonal antibody against GJB2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human GJB2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP36608-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur GJB2

Antigène: GJB2 (Gap Junction Protein, beta 2, 26kDa (GJB2))

Autre désignation: GJB2

Sujet:

Background Information: Gap junctions were first characterized by electron microscopy as regionally specialized structures on plasma membranes of contacting adherent cells. These structures were shown to consist of cell-to-cell channels. Proteins, called connexins, purified from fractions of enriched gap junctions from different tissues differ. The connexins are designated by their molecular mass. Another system of nomenclature divides gap junction proteins into 2 categories, alpha and beta, according to sequence similarities at the nucleotide and amino acid levels. For example, CX43 (MIM 121014) is designated alpha-1 gap junction protein, whereas CX32 (GJB1, MIM 304040) and CX26 are called beta-1 and beta-2 gap junction proteins, respectively. This nomenclature emphasizes that CX32 and CX26 are more homologous to each other than either of them is to CX43.

Gene Name: Gap junction protein, beta 2, 26 kDa

Alternative Symbols: HID, KID, PPK, BAPS, CX26, DFNA3, DFNB1, NSRD1, DFNA3A, DFNB1A

Protein Name: Gap junction beta-2 protein

Poids moléculaire: 25kDa

ID gène: 2706

NCBI Accession: NP_003995

UniProt: P29033

Pathways: Sensory Perception of Sound, Cell-Cell Junction Organization