MCM8 anticorps (N-Term)

N° du produit ABIN2774899

L’anticorps anti-MCM8 Polyclonal Lapin est utilisé pour la détection de MCM8 dans des échantillons de Humain, Rat, Souris, Boeuf (Vache), Cheval, Cobaye, Lapin, Chien et Poisson zèbre (Danio rerio). Il a été validé pour WB.

Aperçu rapide pour MCM8 anticorps (N-Term) (ABIN2774899)

Antigène: MCM8 (Minichromosome Maintenance Deficient 8 (MCM8))

Reactivité: Humain, Rat, Souris, Boeuf (Vache), Cheval, Cobaye, Lapin, Chien, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MCM8 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-MCM8 anticorps

Épitope: N-Term

Fonction: MCM8 Antibody - N-terminal region

Séquence: ELRDAPEKTL ACMGLAIHQV LTKDLERHAA ELQAQEGLSN DGETMVNVPH

Homologie: Cow: 100%, Dog: 92%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 91%, Rat: 100%, Zebrafish: 83%

Attributs du produit: This is a rabbit polyclonal antibody against MCM8. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human MCM8

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8105452

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur MCM8

Antigène: MCM8 (Minichromosome Maintenance Deficient 8 (MCM8))

Autre désignation: MCM8

Sujet:

Background Information: MCM8 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein contains the central domain that is conserved among the MCM proteins. This protein has been shown to co-immunoprecipitate with MCM4, 6 and 7, which suggests that it may interact with other MCM proteins and play a role in DNA replication. Alternatively spliced transcript variants encoding distinct isoforms have been described.

Gene Name: Minichromosome maintenance complex component 8

Alternative Symbols: POF10, C20orf154, dJ967N21.5

Protein Name: DNA helicase MCM8

Poids moléculaire: 92kDa

ID gène: 84515

NCBI Accession: NP_115874

UniProt: Q9UJA3

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA