IBSP anticorps (N-Term)

N° du produit ABIN2774907

Cet anticorps anti-IBSP Polyclonal Lapin (ABIN2774907) détecte spécifiquement IBSP dans WB. L’anticorps est réactif avec des échantillons de Humain et Chien.

Aperçu rapide pour IBSP anticorps (N-Term) (ABIN2774907)

Antigène: IBSP (Integrin-Binding Sialoprotein (IBSP))

Reactivité: Humain, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IBSP est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-IBSP anticorps

Épitope: N-Term

Fonction: IBSP Antibody - N-terminal region

Séquence: SATTLGYGED ATPGTGYTGL AAIQLPKKAG DITNKATKEK ESDEEEEEEE

Homologie: Dog: 79%, Human: 100%

Attributs du produit: This is a rabbit polyclonal antibody against IBSP. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human IBSP

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP36681-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur IBSP

Antigène: IBSP (Integrin-Binding Sialoprotein (IBSP))

Autre désignation: IBSP

Sujet:

Background Information: The protein encoded by the IBSP gene is a major structural protein of the bone matrix. It constitutes approximately 12 % of the noncollagenous proteins in human bone and is synthesized by skeletal-associated cell types, including hypertrophic chondrocytes, osteoblasts, osteocytes, and osteoclasts. The only extraskeletal site of its synthesis is the trophoblast. This protein binds to calcium and hydroxyapatite via its acidic amino acid clusters, and mediates cell attachment through an RGD sequence that recognizes the vitronectin receptor.

Gene Name: Integrin-binding sialoprotein

Alternative Symbols: BSP, BNSP, SP-II, BSP-II

Protein Name: Bone sialoprotein 2

Poids moléculaire: 35kDa

ID gène: 3381

NCBI Accession: NP_004958

UniProt: P21815