THO Complex 4 anticorps (N-Term)

N° du produit ABIN2774915

Cité dans 2 publications. Cet anticorps anti-THO Complex 4 Polyclonal Lapin (ABIN2774915) détecte spécifiquement THO Complex 4 dans WB et IHC. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Boeuf (Vache), Poisson zèbre (Danio rerio) et Chien.

Aperçu rapide pour THO Complex 4 anticorps (N-Term) (ABIN2774915)

Antigène: THO Complex 4 (THOC4)

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Poisson zèbre (Danio rerio), Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp THO Complex 4 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-THO Complex 4 anticorps

Épitope: N-Term

Fonction: THOC4 Antibody - N-terminal region

Séquence: GGGPIRNRPA IARGAAGGGG RNRPAPYSRP KQLPDKWQHD LFDSGFGGGA

Homologie: Cow: 100%, Dog: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against THOC4. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human THOC4

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8113806

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-THO Complex 4 (ABIN2774915)

Ding, Enriquez-Algeciras, Dave, Perez-Pinzon, Bhattacharya: "The role of deimination in ATP5b mRNA transport in a transgenic mouse model of multiple sclerosis." dans: EMBO reports, Vol. 13, Issue 3, pp. 230-6, (2012) (PubMed).

Strässer, Masuda, Mason, Pfannstiel, Oppizzi, Rodriguez-Navarro, Rondón, Aguilera, Struhl, Reed, Hurt: "TREX is a conserved complex coupling transcription with messenger RNA export." dans: Nature, Vol. 417, Issue 6886, pp. 304-8, (2002) (PubMed).

Détails sur THO Complex 4

Antigène: THO Complex 4 (THOC4)

Autre désignation: THOC4

Sujet:

Targeted Subunit: 4

Background Information: THOC4 is a heat stable, nuclear protein and functions as a molecular chaperone. It is thought to regulate dimerization, DNA binding, and transcriptional activity of basic region-leucine zipper (bZIP) proteins.The protein encoded by this gene is a heat stable, nuclear protein and functions as a molecular chaperone. It is thought to regulate dimerization, DNA binding, and transcriptional activity of basic region-leucine zipper (bZIP) proteins.

Gene Name: Aly/REF export factor

Alternative Symbols: ALY, BEF, REF, THOC4, ALY/REF

Protein Name: THO complex subunit 4

Poids moléculaire: 28kDa

ID gène: 10189

NCBI Accession: NP_005773

UniProt: Q86V81