THO Complex 4 anticorps (N-Term)

N° du produit ABIN2774915

Détail du produit anti-THO Complex 4 anticorps

Antigène: THO Complex 4 (THOC4)

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Poisson zèbre (Danio rerio), Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp THO Complex 4 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: GGGPIRNRPA IARGAAGGGG RNRPAPYSRP KQLPDKWQHD LFDSGFGGGA

Homologie: Cow: 100%, Dog: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against THOC4. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human THOC4

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 257 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-THO Complex 4 (ABIN2774915)

Ding, Enriquez-Algeciras, Dave, Perez-Pinzon, Bhattacharya: "The role of deimination in ATP5b mRNA transport in a transgenic mouse model of multiple sclerosis." dans: EMBO reports, Vol. 13, Issue 3, pp. 230-6, (2012) (PubMed).

Strässer, Masuda, Mason, Pfannstiel, Oppizzi, Rodriguez-Navarro, Rondón, Aguilera, Struhl, Reed, Hurt: "TREX is a conserved complex coupling transcription with messenger RNA export." dans: Nature, Vol. 417, Issue 6886, pp. 304-8, (2002) (PubMed).

Détails sur THO Complex 4

Antigène: THO Complex 4 (THOC4)

Autre désignation: THOC4 (THOC4 Produits)

Synonymes: anticorps THOC4, anticorps Aly, anticorps ALY, anticorps ALY/REF, anticorps BEF, anticorps REF, anticorps tho4, anticorps thoc4, anticorps zgc:171753, anticorps Tho4-A, anticorps alyref-a, anticorps thoc4-a, anticorps REF1, anticorps Refbp1, anticorps Thoc4, anticorps Tho4, anticorps Aly/REF export factor, anticorps THO complex 4, anticorps Aly/REF export factor L homeolog, anticorps ALYREF, anticorps Thoc4, anticorps alyref, anticorps alyref.L, anticorps Alyref

Sujet: THOC4 is a heat stable, nuclear protein and functions as a molecular chaperone. It is thought to regulate dimerization, DNA binding, and transcriptional activity of basic region-leucine zipper (bZIP) proteins.The protein encoded by this gene is a heat stable, nuclear protein and functions as a molecular chaperone. It is thought to regulate dimerization, DNA binding, and transcriptional activity of basic region-leucine zipper (bZIP) proteins.
Alias Symbols: ALY, BEF, REF, THOC4, ALY/REF
Protein Interaction Partner: TP53, AKT1, NEDD1, THOC3, NCBP1, THOC2, CEP250, THOC5, DDX39B, STAU1, UBC, MDM2, SUZ12, EED, RNF2, FBXO6, CD81, ICAM1, IGSF8, PAN2, VCAM1, ITGA4, IL7R, FN1, CBX8, EIF4A3, MAGOH, PAXIP1, TRIP12, TRIP13, UBE2I, SF3B4, TLE3, YBX1, HNRNPM, ERCC4, ATP6V1E1, UB
Protein Size: 257

Poids moléculaire: 28 kDa

ID gène: 10189

NCBI Accession: NM_005782, NP_005773

UniProt: Q86V81