RNF6 anticorps (N-Term)

N° du produit ABIN2774918

L’anticorps Lapin Polyclonal anti-RNF6 a été validé pour WB. Il convient pour détecter RNF6 dans des échantillons de Humain, Rat, Boeuf (Vache), Cheval, Porc, Chien, Cobaye et Lapin.

Aperçu rapide pour RNF6 anticorps (N-Term) (ABIN2774918)

Antigène: RNF6 (RING Finger Protein 6 (RNF6))

Reactivité: Humain, Rat, Boeuf (Vache), Cheval, Porc, Chien, Cobaye, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RNF6 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-RNF6 anticorps

Épitope: N-Term

Séquence: LQQRLDGVKE QLASQPDLRD GTNYRDSEVP RESSHEDSLL EWLNTFRRTG

Homologie: Cow: 85%, Dog: 86%, Guinea Pig: 85%, Horse: 86%, Human: 100%, Pig: 86%, Rabbit: 85%, Rat: 86%

Attributs du produit: This is a rabbit polyclonal antibody against RNF6. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human RNF6

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 685 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur RNF6

Antigène: RNF6 (RING Finger Protein 6 (RNF6))

Autre désignation: RNF6

Sujet: RNF6 contains a RING-H2 finger motif. Deletions and mutations in this gene were detected in esophageal squamous cell carcinoma (ESCC), suggesting that this protein may be a potential tumor suppressor. Studies of the mouse counterpart suggested a role of this protein in the transcription regulation that controls germinal differentiation. The protein encoded by this gene contains a RING-H2 finger motif. Deletions and mutations in this gene were detected in esophageal squamous cell carcinoma (ESCC), suggesting that this protein may be a potential tumor suppressor. Studies of the mouse counterpart suggested a role of this protein in the transcription regulation that controls germinal differentiation. Multiple alternatively spliced transcript variants encoding the same protein are observed.
Alias Symbols: DKFZp686P0776
Protein Interaction Partner: UBE2D1, AR, LDB1, UBC, tat, UBE2H,
Protein Size: 685

Poids moléculaire: 78 kDa

ID gène: 6049

NCBI Accession: NM_005977, NP_005968

UniProt: Q9Y252

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Cell Size