RNF6 anticorps (N-Term)

N° du produit ABIN2774918

L’anticorps anti-RNF6 Polyclonal Lapin est utilisé pour la détection de RNF6 dans des échantillons de Humain, Rat, Boeuf (Vache), Cheval, Porc, Chien, Cobaye et Lapin. Il a été validé pour WB.

Aperçu rapide pour RNF6 anticorps (N-Term) (ABIN2774918)

Antigène: RNF6 (RING Finger Protein 6 (RNF6))

Reactivité: Humain, Rat, Boeuf (Vache), Cheval, Porc, Chien, Cobaye, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RNF6 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-RNF6 anticorps

Épitope: N-Term

Fonction: RNF6 Antibody - N-terminal region

Séquence: LQQRLDGVKE QLASQPDLRD GTNYRDSEVP RESSHEDSLL EWLNTFRRTG

Homologie: Cow: 85%, Dog: 86%, Guinea Pig: 85%, Horse: 86%, Human: 100%, Pig: 86%, Rabbit: 85%, Rat: 86%

Attributs du produit: This is a rabbit polyclonal antibody against RNF6. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human RNF6

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP43064-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur RNF6

Antigène: RNF6 (RING Finger Protein 6 (RNF6))

Autre désignation: RNF6

Sujet:

Background Information: RNF6 contains a RING-H2 finger motif. Deletions and mutations in this gene were detected in esophageal squamous cell carcinoma (ESCC), suggesting that this protein may be a potential tumor suppressor. Studies of the mouse counterpart suggested a role of this protein in the transcription regulation that controls germinal differentiation. The protein encoded by this gene contains a RING-H2 finger motif. Deletions and mutations in this gene were detected in esophageal squamous cell carcinoma (ESCC), suggesting that this protein may be a potential tumor suppressor. Studies of the mouse counterpart suggested a role of this protein in the transcription regulation that controls germinal differentiation. Multiple alternatively spliced transcript variants encoding the same protein are observed.

Gene Name: Ring finger protein (C3H2C3 type) 6

Alternative Symbols: DKFZp686P0776

Protein Name: E3 ubiquitin-protein ligase RNF6

Poids moléculaire: 78kDa

ID gène: 6049

NCBI Accession: NP_005968

UniProt: Q9Y252

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Cell Size